-
Combined Tacrolimus, Belatacept Regimen Improves Post-Kidney Transplant Outcomes
30 Jan 2025 14:02 GMT
… nephrologist at Beth Israel Deaconess Medical Center, and colleagues wrote. … of kidney transplant recipients on belatacept versus tacrolimus immunosuppression, investigators … on either tacrolimus or belatacept-based maintenance immunosuppression were …
-
Citryll Announces the Appointment of Maarten Kraan as Chief Medical Officer
13 Feb 2024 10:17 GMT
… , a clinical-stage biotech company developing first-in … the launch of Nulojix (belatacept) for delayed graft function … opportunity to improve current treatment paradigms for rheumatoid arthritis … more than 25 years of pharmaceutical experience. Most recently, …
-
Human medicines European public assessment report (EPAR): Nulojix, belatacept, Date of authorisation: 17/06/2011, Revision: 21, Status: Authorised
12 Dec 2023 20:21 GMT
The most common serious side effects of Nulojix seen in more than 2% of patients are urinary-tract infection (infection of the structures that carry urine), cytomegalovirus infection, pyrexia (fever), increased blood creatinine (a marker of kidney problems …
-
Endpoints and Trial Designs to Advance Drug Development in Kidney Transplantation - 11/09/2023
24 Aug 2023 23:04 GMT
… and trial design to promote drug development in kidney transplantation. The last drug FDA … rejection in kidney transplant was belatacept in 2011. It is well … , impact of treatment and grade of rejection.
Non-inferiority Trials: identifying clinically …
-
Cardiovascular Risk in Kidney Transplant Recipients After Conversion to Belatacept From a Calcineurin Inhibitor
13 Apr 2023 13:21 GMT
… Journal of kidney medicine by Bredewold, et al.
A belatacept-based immunosuppressive … CV risk of belatacept and CNI (predominantly tacrolimus) treatments. Trial design: prospective, randomized …
-
Artax Biopharma Appoints D. Scott Batty, Jr., M.D. as Chief Medical Officer
29 Jun 2022 15:34 GMT
… Phase 1 clinical trial evaluating AX-158, … Director of Medical Affairs for the belatacept immunosuppression program … pathologies in which medical treatments result in immune reactions … biotechnology company transforming T Cell-mediated disease treatment …
-
Lung Transplant Rejection Pipeline Analysis | Clinical Trials Evaluation Research Report 2022 by DelveInsight
31 Mar 2022 17:00 GMT
… treatment therapies.
Some of the key pharmaceutical companies working to develop potential drug … Belatacept, and others are under development in different phases of clinical trials … clinical trial designed … Miromatrix Medical, Lung Biotechnology PBC, …
-
Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients
29 Mar 2022 13:28 GMT
… included transplantation data, vaccination characteristics, recent immunosuppressive medication, and routine laboratory test … response were MPA dose and belatacept treatment. Contrastingly, higher BMI, younger age …
-
Study compares heterologous and homologous third vaccination in kidney transplant recipients
01 Mar 2022 02:58 GMT
… a single-blinded trial of homologous and heterologous vaccination in kidney transplant … vector vaccine booster groups. These patients were on immunosuppressive medications like belatacept, tacrolimus …
-
Response to COVID-19 vaccine booster in seronegative kidney transplant recipients
01 Feb 2022 01:26 GMT
… population. Thus, intensified vaccination schedules with early … mofetil (MMF) and belatacept present similar drawbacks among … vaccination doses in KTRs was found to be related to immunosuppressive drug … use, especially MMF.
With the third vaccination …