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Taurine-Modified Gossypol Exerts Dual Anti-Hepatocellular Carcinoma Effects by Inactivating PI3K/AKT Pathway and Targeting FASN-Mediated Lipid Metabolism in Regulatory T Cells
15 Dec 2025 10:47 GMT
… will construct HCC xenograft models (eg, patient-derived xenografts) or genetically engineered … tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response …
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Targeting Nuclear Receptors: A New Frontier in Brain Cancer Therapy
16 Sep 2025 14:43 GMT
… employing patient-derived xenografts and immunocompetent models … distinguish and drive diverse brain tumor phenotypes. The integration … in brain cancer therapysurgical and radiotherapy advancementstherapeutic intervention for brain tumorstranscription …
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Focused Ultrasound-Mediated Temozolomide Delivery Into Intact Blood-Brain Barrier Tissue Improves Survival in Patient-Derived Xenograft Model of Glioblastoma
28 Aug 2025 10:36 GMT
… most prevalent and aggressive primary brain tumor in adults, characterized by rapid … and survival in an orthotopic xenograft mouse model.
MethodsHuman primary GBM … mice to establish an orthotopic xenograft model. FUS was applied 1 …
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A Minireview on Nanosized Hypericin-Based Inducer of Immune Cell Death Under ROS-Based Therapies
08 Dec 2025 22:04 GMT
… -2 nasopharyngeal carcinoma cells and xenografts,38 whereas human dermal fibroblasts … therapy mediated immune therapy of brain tumors. Neuroimmunol Neuroinflamm. 2018;5:27 …
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Brain tumors exploit body's daily rhythms to fuel growth
18 Dec 2024 15:43 GMT
… most common and aggressive malignant brain tumor in adults, with limited survival … in vivo experiments involved orthotopic xenografts, in which human and mouse …
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Small brain-penetrating molecule offers hope for treating aggressive brain tumors
21 Nov 2024 12:28 GMT
… glioblastoma, an aggressive form of brain tumor.
The study found that gliadin … the most lethal forms of brain cancer and is known for its … cell lines and patient-derived xenograft models. Additionally, the pharmacokinetic studies …
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Nano-Drug Delivery Systems Targeting MMPs: A Promising Treatment for Gliomas
05 Dec 2025 08:40 GMT
… represents the most formidable brain cancer due to its highly … loaded nanoparticles into glioblastoma xenograft mice using CED. … transiently disrupt the Blood-Brain Tumor Barrier (BBTB) and … drug in the complex brain tumor microenvironment, while reducing …
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Sylvester Brain Tumor Institute Launches to Personalize Brain Cancer Treatment
15 May 2024 06:56 GMT
… of the Sylvester Brain Tumor Institute (SBTI) to elevate brain cancer care and research … in South Florida and beyond.
“The Sylvester Brain Tumor … cancer cells, and patient-derived xenografts, where tumor cells are re …
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Sylvester Cancer Launches New Brain Tumor Institute to Personalize Brain Cancer Treatment
09 May 2024 14:17 GMT
… , personalized care for brain cancer patients.
“The Sylvester Brain Tumor Institute will further enable … cancer cells, and patient-derived xenografts, where tumor cells are re … using patient-derived organoids and xenografts, those efforts will be bolstered …
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Research: Deadly brain cancer can mimic healthy neurons
10 Feb 2024 19:24 GMT
… .
Glioblastoma, for example, an incurable brain cancer, is characterized by cells that … dish and a patient-derived xenograft tumor in mice. In both …