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Therapeutic Targeting in Ovarian Cancer: Nano-Enhanced CRISPR/Cas9 Gene Editing and Drug Combination Therapy
29 Mar 2025 11:12 GMT
… virus integration site 1; BRCA2, breast cancer susceptibility gene … . Additionally, TRP53 and BRCA2 knockout in ID8 intraperitoneal … et al. Genetic interactions among Brca1, Brca2, Palb2, and Trp53 in … grade serous carcinoma targeting Brca1, Pten and Nf1, …
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Novel Protein Configuration Could Pave the Way for Innovative Cancer Therapies
02 Apr 2025 21:30 GMT
… from genetic vulnerabilities such as BRCA1 and BRCA2 mutations. Traditional cancer treatments … address the specific vulnerabilities of BRCA1 and BRCA2 deficient cancers. To consolidate …
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What the Science of Gene Inheritance Reveals About the Humans Behind It
02 Apr 2025 11:25 GMT
… (FMR1), of breast cancer (BRCA1 and BRCA2), and of cognitive decline due …
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Role of EFNAs in Shaping the Tumor Immune Microenvironment and Their Impact on Pancreatic Adenocarcinoma Prognosis
02 Apr 2025 00:30 GMT
… Q, Tang X, et al. BRCA2 promoter hypermethylation as a biomarker …
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Institute researchers find links between exposure to Carcinogens and aromatics released from gasoline
01 Apr 2025 23:38 GMT
… passed down to offspring. BRCA1 and BRCA2 are two of the most …
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International group publishes first clinical guidance on polygenic risk scores for breast cancer
01 Apr 2025 21:28 GMT
… pathogenic variants in genes like BRCA1 or BRCA2 or have a strong …
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Jill Martin On How Her Battle With Breast Cancer Battle Has Given Her Purpose
01 Apr 2025 14:02 GMT
… that Martin had inherited the BRCA2 mutation – not from her mother …
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Today’s Jill Martin Recalls Harrowing Battle with Breast Cancer: ‘I Still Find It Hard to Believe’ (Exclusive)
01 Apr 2025 14:02 GMT
… that Martin had inherited the BRCA2 mutation—not from her mother …
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Can wearing underwire bra cause breast cancer? Doctors bust 11 dangerous myths
31 Mar 2025 11:25 GMT
… to inherited genetic mutations like BRCA1 and BRCA2. Dr Salkar adds that … : If you have the BRCA1 or BRCA2 gene mutation, you will definitely … develop breast cancer.
Truth: While BRCA1 …
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Genomic Insights Into Early Relapsed Breast Cancer: Prognostic Challenges and Mutation Landscape
28 Mar 2025 22:19 GMT
… ), with SYK, RECQL4, and BRCA2 mutations each present in 11% … (11%), RECQL4 (11%), and BRCA2 (11%). This profile differs notably … of SYK, RECQL4, and BRCA2 in early-relapsing patients exceed … ,20 while RECQL4 and BRCA2 mutations compromise DNA repair …