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<![CDATA[FDA Accepts NDA for Zidesamtinib in Advanced ROS1+ NSCLC]]>
20 Nov 2025 23:45 GMT
… Drilon, ARROS-1 trial investigator, added.3 … (Lorbrena), repotrectinib (Augtyro), crizotinib (Xalkori), entrectinib (Rozlytrek), … 2024 European Society for Medical Oncology (ESMO) … FDA acceptance of new drug application for zidesamtinib for the treatment …
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<![CDATA[Your Genes, Your Treatment: Biomarker Testing and Lung Cancer ]]>
20 Nov 2025 23:11 GMT
… an individually tailored treatment approach.
“Biomarker … University School of Medicine, and associate cancer … brigatinib) Zykadia (ceritinib), Xalkori (crizotinib), Lorbrena (lorlatinib), Ensacove (ensartinib … shared how antibody-drug conjugates have become …
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<![CDATA[FDA Accepts NDA for Zidesamtinib in ROS1+ Advanced NSCLC After a Prior TKI]]>
21 Nov 2025 17:43 GMT
… TKI in the form of crizotinib or entrectinib, with or … data from the ARROS-1 trial, which showed that patients … global, first-in-human trial evaluating zidesamtinib in patients with … FDA acceptance of new drug application for zidesamtinib for the treatment …
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<![CDATA[FDA Accepts NDA for Zidesamtinib in Pretreated Advanced ROS1+ NSCLC]]>
20 Nov 2025 20:32 GMT
… 1. Results from the trial were shared in the … prior ROS1 TKI of either crizotinib (Xalkori) or entrectinib (Rozlytrek … Early Drug Development Service and a thoracic medical oncologist … FDA acceptance of new drug application for zidesamtinib for the treatment …
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<![CDATA[FDA Clears Oncomine Dx Target Test as Companion Diagnostic for Sevabertinib in NSCLC]]>
21 Nov 2025 00:11 GMT
… received prior treatment, including HER2-targeted antibody-drug conjugates … ;2 SOHO-01 trial showed strong responses … (Gavreto), selpercatinib (Retevmo), crizotinib (Xalkori)
Cholangiocarcinoma: Ivosidenib (Tibsovo … Division of Internal Medicine at The …
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<![CDATA[Phase 2 Trials Support NCCN’s Inclusion of Combinations for nccRCC]]>
19 Nov 2025 02:43 GMT
… and the FDA approved having the clinical trial data added … seen in other trials.
These were the treatment-related adverse … comparing sunitinib with cabozantinib, crizotinib, and savolitinib in advanced … sunitinib in first-line treatment of advanced renal cell …
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Nuvalent Announces Positive Topline Pivotal Data from ALKOVE-1 Clinical Trial of Neladalkib for TKI Pre-treated Patients with Advanced ALK-positive NSCLC
17 Nov 2025 12:25 GMT
… only. No patients received crizotinib as their only ALK … results at a future medical meeting.
Webcast and Conference … S. Food and Drug Administration (FDA) for the treatment of patients with … ALKAZAR Phase 3 Clinical Trials
The ALKOVE-1 trial ( NCT05384626 ) …
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<![CDATA[Dr Orloff on OS Outcomes With Darovasertib Plus Crizotinib in Metastatic Uveal Melanoma]]>
13 Nov 2025 03:20 GMT
… Melanoma at the Sidney Kimmel Medical College of Thomas Jefferson … 01 trial (NCT03947385) investigating darovasertib plus crizotinib (Xalkori) for the first-line treatment … preliminary data with darovasertib plus crizotinib suggest a profound advancement in …
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<![CDATA[Darovasertib Plus Crizotinib Could Represent Systemic Therapy Intended for Broader Metastatic Uveal Melanoma Population]]>
07 Nov 2025 17:32 GMT
… ]. To have a drug that finally shows some … this trial, darovasertib was being combined with either crizotinib, and … However, looking at the trials that got tebentafusp approved … your typical cancer treatment with general cancer treatment–related toxicities, …
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<![CDATA[Clinical and Logistical Factors Determine Treatment Choice for nccRCC]]>
04 Nov 2025 00:58 GMT
… professor of medicine at University of Chicago Medicine, asked … drug-drug interactions and polypharmacy with patients managing lots of pills … treat with these treatment paradigms we just … comparing sunitinib with cabozantinib, crizotinib, and savolitinib in …