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    • Crizotinib

Crizotinib Newsletter
  • Public consultation on cancer medicines closes soon 21 Jan 2025 21:33 GMT

    … 27. Pharmac’s director pharmaceuticals, Geraldine MacGibbon, says … called acute lymphoblastic leukaemia crizotinib (branded as Xalkori) … increase access to ADHD medicines. The consultation is … and funding restrictions stimulant treatments. This closes February …

  • Consultations For Cancer And ADHD Medicines Close Soon 21 Jan 2025 20:43 GMT

    … MacGibbon, Pharmac’s Director Pharmaceuticals, says there’s just … called acute lymphoblastic leukaemia crizotinib (branded as Xalkori) … increase access to ADHD medicines. The consultation is … and funding restrictions stimulant treatments. This closes Tuesday …

  • FDA Drug Approvals Q4 2024 16 Jan 2025 15:45 GMT

    … , open-label (eXALT3) trial (N = 290). Treatment with ensartinib resulted in … free survival (PFS) compared with crizotinib (25.8 vs. 12. … This rearrangement is associated with drug resistance and a poor prognosis … was granted by the FDA based on the HERIZON- …

  • Roles of SPOCK1 in the Formation Mechanisms and Treatment of Non-Small-Cell Lung Cancer and Brain Metastases from Lung Cancer 15 Jan 2025 20:05 GMT

    … been criticized by some doctors. It is certain that … BBB: Researchers at Harvard Medical School found that neurons … conduct larger randomized controlled trials comparing HA-CRT and … develop drug resistance within a year after starting crizotinib treatment.43 …

  • July - September 2024 | Potential Signals of Serious Risks/New Safety Information Identified by the FDA Adverse Event Reporting System (FAERS) 30 Dec 2024 19:56 GMT

    … generic version of the drug product(s), if there … crizotinib) capsules Xalkori (crizotinib) oral pellets Severe cutaneous adverse reaction FDA … contribute to wrong drug errors FDA is evaluating the … co-packaged Drug-induced liver injury FDA is evaluating the …

  • OncLive’s December Roundup of Key FDA Approvals in Oncology 30 Dec 2024 20:26 GMT

    … from the phase 3 ADRIATIC trial (NCT03703297). The immunotherapy … multisponsor inspection of the pharmaceutical company’s third-party … or death by 44% vs crizotinib (Xalkori). The median … treatment in the first-line setting,” Giovanni Selvaggi, chief medical

  • FDA Grants Taletrectinib Priority Review for Advanced ROS1+ NSCLC 23 Dec 2024 21:00 GMT

    … 2, Chinese TRUST-I trial (NCT04395677) evaluating the safety … of Medical Oncology (ESMO) Congress .4 In both trials, patients … whom were previously treated with crizotinib (Xalkori) or entrectinib ( … new drug application for taletrectinib for the treatment of …

  • FDA Approves Ensacove for ALK-Positive NSCLC 19 Dec 2024 00:48 GMT

    Drug Administration has approved Ensacove (ensartinib) for the treatment … receive Ensacove or Xalkori (crizotinib). Glossary: Progression-free survival … and 100 current clinical trials in the United States … . Stephen Liu, a medical oncologist who leads the …

  • FDA Approves Ensartinib in Metastatic ALK-Positive NSCLC 18 Dec 2024 21:11 GMT

    … from the phase 3 eXalt3 trial (NCT02767804), in which investigators evaluated … the ensartinib and crizotinib groups. AEs leading to treatment discontinuation with ensartinib … .3523 U.S. Food and Drug Administration (FDA) has accepted the new …

  • FDA approves ensartinib for ALK-positive locally advanced or metastatic non-small cell lung cancer 18 Dec 2024 21:08 GMT

    … Ensacove will be posted on Drugs@FDA. Efficacy and Safety Efficacy … randomized, active-controlled, multicenter trial in 290 patients with locally … PFS improvement compared to crizotinib with a hazard ratio … use of any medicine and device to FDA’s MedWatch …

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