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Tumor Microenvironment Modulation by Tumor-Associated Macrophages: Implications for Neoadjuvant Chemotherapy Response in Breast Cancer
21 Feb 2025 14:01 GMT
… collected from hospital medical records. The … epirubicin, and cyclophosphamide (TEC); epirubicin and cyclophosphamide followed by … response to treatment, potentially influencing drug resistance, … and neoadjuvant breast cancer treatments: a systematic review …
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Phase III AMPLIFY Trial Shows Calquence Plus Venetoclax Significantly Improves Survival in Untreated CLL
20 Feb 2025 20:48 GMT
… AMPLIFY trial (NCT03836261) published in The New England Journal of Medicine.1 … fludarabine–cyclophosphamide–rituximab (n = 143) or bendamustine–rituximab (n = 147). The trial … #47;press-announcements/fda-approves-new-treatment-adults-mantle-cell-lymphoma …
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Key Trials From ASH 2024 Impact Treatment for Plasma Cell Disorders Going Forward
20 Feb 2025 17:55 GMT
… School of Medicine
NYU Perlmutter Cancer Center
NYU … myeloma.
What trials presented affected patients … of Medicine, where they compared daratumumab, cyclophosphamide, bortezomib … ; ANDROMEDA Trial Investigators. Daratumumab-based treatment for immunoglobulin …
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Ciltacabtagene Autoleucel for the Treatment of Relapsed/Refractory Multiple Myeloma: Efficacy, Safety, and Place in Therapy
19 Feb 2025 08:14 GMT
… pivotal CARTITUDE trials used fludarabine and cyclophosphamide, the use … Sanofi, HopeAI, Adaptive biotechnologies, Bristol-Myers Squibb, … 47;/www.fda.gov/vaccines-blood-biologics… multiple myeloma current treatment algorithms. Blood Cancer J. 2022 …
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Injectable Drug Delivery Devices Market Size Expected to Reach USD 1,217 Bn by 2034
18 Feb 2025 17:21 GMT
… and ongoing Vild cancer researchers and clinical trials are lubricating the … to homecare treatment settings. Browse More Research Reports ; Drug Discovery Market … from Nexus Pharmaceuticals to boost its production of injectable medications. This FDA-approved …
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FDA accepts IND for allogenic CAR T-cell therapy that could bypass lymphodepletion
18 Feb 2025 13:18 GMT
… Healio
The FDA has accepted an investigational new drug application … , the need for pre-treatment lymphodepletion, a process that … of increasingly clever innovations in medicine,” she said. “To … patients on a dose of cyclophosphamide.
“Demonstrating the power …
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KN026-Docetaxel Combo Shows Efficacy, Safety in HER2+ Metastatic Breast Cancer
17 Feb 2025 19:02 GMT
… Radiotherapy at Cancer Hospital, Harbin Medical University in … treatment option for HER2-positive recurrent/metastatic breast cancer … had previously received were cyclophosphamide (50.9%), docetaxel … #47;www.accessdata.fda.gov/drugsatfda_docs/nda …
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Acalabrutinib-Venetoclax Prolongs Survival in Previously Untreated Leukemia
21 Feb 2025 22:08 GMT
… of Medicine.
Jennifer R. Brown, M.D., from Dana-Farber Cancer Institute … a phase 3, open-label trial involving patients with CLL aged … 's choice of fludarabine-cyclophosphamide-rituximab or bendamustine-rituximab (291 …
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CRISTALLO Study of Venetoclax/Obinutuzumab Achieves Superior MRD in CLL
21 Feb 2025 03:54 GMT
… used for the treatment of patients with treatment-naive chronic lymphocytic leukemia … known safety profiles of each drug. Infusion-related reactions were seen … a phase III trial of venetoclax-obinutuzumab versus fludarabine, cyclophosphamide and rituximab …
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Study Finds Recent Falls, Inability to Balance on Left Leg Indicate OS Decrease in NHL
19 Feb 2025 01:12 GMT
… the Department of Medicine at Roswell Park Comprehensive Cancer Center, said during … unfavorable outcomes,” Herr stated.
The trial evaluated data from 91 patients … , 82% received fludarabine and cyclophosphamide, 72% were treatment resistant at ACT, and …