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Allogene Therapeutics’ ALLO-329 Snags FDA Fast Track Designations for 3 Rheumatology Indications
07 Apr 2025 23:18 GMT
… identifier pending).2 The trial will also include patients … which patients will receive cyclophosphamide alone for lymphodepletion and … development and the chief medical officer at Allogene.1 … FDA orphan drug designation for its ULSC program for the treatment …
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Allogene Granted Three U.S. FDA Fast Track Designations (FTD) for ALLO-329, a Next-Generation Dual-Targeted CD19/CD70 Allogeneic CAR T, for the Treatment of Lupus, Myositis and Scleroderma
07 Apr 2025 12:30 GMT
… ALLO), a clinical-stage biotechnology company pioneering the development of … AlloCAR T™) products for cancer and autoimmune disease, today … Food and Drug Administration (FDA) for the treatment of adult … using a dose of cyclophosphamide alone, which is used …
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Strong 1-Year Survival Shown With MMUD Peripheral Blood Stem Cell Transplants
08 Apr 2025 15:18 GMT
… 2 ACCESS trial (NCT04904588).1
The ACCESS trial assessed posttransplant cyclophosphamide as graft … approach in providing life-saving treatment, particularly for ethnically diverse … underrepresented in bone marrow transplant trials due to various barriers. …
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New mum finds lump while breastfeeding as 'blocked duct' turns out to be cancer
06 Apr 2025 04:40 GMT
… doctors, the mum-of-three discovered the lump was breast cancer … Tumi underwent gruelling treatment involving a … treatment called ECT – a combination of three drugs including cyclophosphamide and docetaxel which Cancer … I think my cancer treatment changed his …
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Preclinical Evaluation Of Novel Drug Candidates Against SLE In NZB/W F1 Mouse Models
05 Apr 2025 12:59 GMT
… advancements in autoimmune research, effective treatment options for SLE remain limited … explore the efficacy of Cyclophosphamide—a standard treatment for SLE—within this … ultimately contributing to more effective treatment strategies for patients living with …
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R-DA-EDOCH/R-DHAP Induction Yields Responses and MRD Negativity in Young, High-Risk MCL Population
08 Apr 2025 13:31 GMT
… , dexamethasone, doxorubicin, cyclophosphamide, and vincristine) alternated … trial (NCT02858804), which were published in Cancer Biology & Medicine … trials.
The open-label, nonrandomized BDH-MCL01 trial … n = 11), treatment-related secondary leukemia …
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Popat Covers Itacitinib and GVHD Prevention Trial Results
03 Apr 2025 20:47 GMT
… and Cellular Therapy, Division of Cancer Medicine at The University of Texas … Anderson Cancer Center, discusses promising findings from a phase 2 trial … evaluating the JAK inhibitor itacitinib (INCB039110) combined with post-transplant cyclophosphamide …
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JAMA: Oral mizoribine with glucocorticoids safe and effective for treatment initiation in lupus nephritis
03 Apr 2025 17:16 GMT
… Medical Association showed that when taken with glucocorticoids for induction treatment … extensive, long-term clinical trials with mizoribine, though. … against IV cyclophosphamide as induction treatment for Chinese … for inclusion. The trial concluded on March …
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Overcoming Challenges and Advancing CAR-T Therapy for Myeloma
04 Apr 2025 21:15 GMT
… proteasome inhibitors and immunomodulatory drugs, are factors, with … intensive chemotherapy, high-dose cyclophosphamide, levodopa or plasmapheresis.
… oncologists and academic treatment centers should partner … trials are ongoing.
For more news on cancer …
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GMALL Protocol in Rare Lymphoma: The Good, Bad, and Toxic
08 Apr 2025 07:27 GMT
… at the University Medical Center Hamburg-Eppendorf … involvement in 18%.
Treatment consisted of 4 … chemotherapy incorporating hyperfractionated cyclophosphamide/ifosfamide, … relationships with various pharmaceutical companies. Additional disclosures …