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'Separate treatment protocols needed for acquired and congenital hemophilia A'
24 Apr 2025 06:16 GMT
… pathogenesis, clinical presentation, and treatment strategies.
“Acquired hemophilia A … mainstay of treatment for acquired hemophilia A. These drugs promote … Common examples include recombinant activated factor VII (rFVIIa) and activated prothrombin …
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FDA approves fitusiran for hemophilia A, B patients aged 12 years and up
28 Mar 2025 22:15 GMT
… patients (with or without factor VII or IX inhibitors) who … FDA’s Center for Drug Evaluation and Research.
“This new treatment … received on-demand treatment with medicines known as “bypassing … the two randomized clinical trials.
Estimated annualized bleeding …
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Hemab Therapeutics Presents Interim Data from Ongoing Phase 2 Study of HMB-001 as First Ever Prophylactic Treatment in Glanzmann Thrombasthenia and Preclinical Data from HMB-002 in Von Willebrand Disease at the 2025 EAHAD Annual Congress
07 Feb 2025 14:13 GMT
… a clinical-stage biotechnology company developing novel … and support future clinical trials.
Hemab' … of those bleeds requiring medical treatment. These bleeding episodes … like Glanzmann thrombasthenia, Factor VII Deficiency, Von Willebrand Disease …
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The Mechanisms of Sepsis Induced Coagulation Dysfunction and Its Treatment
03 Feb 2025 05:03 GMT
… TFPI-related medications have concluded clinical trials in recent … complement activation. Pharmacological treatments, including statins, vitamin C, … transfusions, and vasoactive drugs to maintain stable … FVa, Factor Va; FVII, Factor VII; FVIIa, Factor VIIa; …
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Recent Advances in Pathogenesis and Anticoagulation Treatment of Sepsis-Induced Coagulopathy
17 Jan 2025 14:00 GMT
… the US Food and Drug Administration (FDA) in 2001.136–138 … inhibitor is an inhibitor of factor VII-activating protease. J Thromb … sepsis: potential new options for treatment. Pharmaceuticals. 2023;16(2):271. … model. Artif Cells Nanomed Biotechnol. 2023;51(1):33 …
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Hemophilia Patients In Maharashtra Face Crisis As Government Hospitals Run Out Of Medicines
13 Dec 2024 20:09 GMT
… saving medications, including Factor VIII, Factor IX, Factor VII, and … unable to receive the treatment they desperately need. Additionally … endure frequent and disruptive treatments. “This neglect … state funding for hemophilia treatment, which currently stands …
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TiumBio Submits CTA for Phase 1b Clinical Trial of TU7710, a Long-acting Recombinant Activated Factor VII, in Hemophilia A or B Patients
26 Mar 2024 23:25 GMT
… the Spanish Agency of Medicines and Medical Products (AEMPS) to … treatment options available on the market, including the leading drug … global Phase 2 clinical trials. TU2218 is a first … clinical-trial-of-tu7710-a-long-acting-recombinant-activated-factor-vii- …
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Bioengineering the body for self-produced medicine
12 Jul 2024 09:04 GMT
… produce and release proteins or drugs into the bloodstream. This approach … ’ bodies make their medicines, potentially offering advantages over intravenous treatments. Daniel Siegwart … encoding a secretory SP from Factor VII, a protein in blood clotting …
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Engineered mRNA turns your body into a drug-making biofactory
05 Jul 2024 16:23 GMT
… as a gene-based treatment for a range of diseases … produces secretory SP derived from Factor VII, a protein involved in … modified mRNA coding for the medication etanercept, their skin plaques … effects associated with, protein drugs currently given by infusion. …
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TiumBio Presents Promising Clinical Data from Phase 1 of its Hemophilia Treatment Candidate TU7710 at ISTH 2024
24 Jun 2024 15:09 GMT
… , long-acting recombinant activated factor VII, demonstrated a 5 to … NovoSeven, a conventional hemophilia treatment for patients who develop … there are significant unmet medical needs for patients and … global Phase 2 clinical trials. TU2218 is a first …