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Tislelizumab Plus Chemo Expands First-Line ESCC Treatment Paradigm
01 Apr 2025 01:31 GMT
… from phase 3 RATIONALE-306 trial (NCT03783442), as well as … in the Department of Medicine at the University of … PD-1 antibody with 5-fluorouracil [5-FU]–based chemotherapy … for patients and expands their treatment possibilities.
References
Tevimbra approved …
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Merck’s Investigational Subcutaneous Pembrolizumab With Berahyaluronidase Alfa Demonstrates Noninferior Pharmacokinetics Compared to Intravenous (IV) KEYTRUDA® (pembrolizumab) in Pivotal 3475A-D77 Trial
27 Mar 2025 15:16 GMT
… .S. Food and Drug Administration (FDA) has accepted for … fluorouracil (FU), is indicated for the first-line treatment … the development of important medicines and vaccines. We aspire to … fluctuations; the impact of pharmaceutical industry regulation and health …
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Global Submission Seeks Approval for Sugemalimab Treatment in NSCLC
25 Mar 2025 02:30 GMT
… press release from CStone Pharmaceuticals.
The application is … unique advantage over similar drugs.
For the patients … indications by The National Medical Products Administration of China … fluorouracil and platinum-based chemotherapy for the first-line treatment …
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Vyloy pioneers new era in metastatic gastric cancer treatment with Claudin 18.2 targeting
25 Mar 2025 01:31 GMT
… -negative, creating a high unmet medical need for targeted antitumor therapies … and mFOLFOX6 (oxaliplatin, leucovorin, and fluorouracil) achieved a median progression-free … Food and Drug Safety (MFDS) as a first-line treatment for patients …
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Cstone Submits Application To The European Medicines Agency For New Indication Of Sugemalimab In Stage III Non-Small Cell Lung Cancer
24 Mar 2025 04:00 GMT
… -301 Phase III trial , a multicenter, randomized … fluorouracil and platinum-based chemotherapy as first-line treatment … -drug conjugates (ADCs), multispecific antibodies, immunotherapies, and precision medicines. … .
SOURCE CStone Pharmaceuticals
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US-based Nigerian scientist’s discovery could revolutionise prostate cancer treatment
21 Mar 2025 19:51 GMT
… experts in health and internal medicine, shows that the molecule can … designed to deliver 5-fluorouracil, an anticancer drug, directly to tumor cells … invests in pharmaceutical research and crystallography, we can develop better treatments and …
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Dr Rao on the Current Treatment Landscape in Localized Anal Cancer
21 Mar 2025 14:45 GMT
… of trials.”
Sheela Rao, MBBS, MD, FRCP, consultant medical oncologist … clinical trials, she explains.
Regarding localized disease, common treatment had … ACT II trials. Of note, the ACT I trial introduced … 1 and 29, with fluorouracil at 1000 mg/ …
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FDA Grants Standard Approval to Pembrolizumab Plus Trastuzumab/Chemo for HER2+, PD-L1+ Gastric Cancer
19 Mar 2025 20:36 GMT
… and either fluorouracil plus cisplatin … Center Baylor University Medical Center, chief … trial met dual primary endpoint of overall survival (OS) as first-line treatment … 47;www.fda.gov/drugs/;resources-information-approved-drugs/fda-grants- …
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FDA approves pembrolizumab for HER2 positive gastric or gastroesophageal junction adenocarcinoma expressing PD-L1 (CPS ≥1)
19 Mar 2025 17:49 GMT
… double-blind, placebo-controlled trial enrolling 698 patients with … with trastuzumab and either fluorouracil plus cisplatin or … of treatment.
This application was granted orphan drug designation. FDA expedited … of any medicine and device to FDA’s MedWatch …
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Core-Shell Magnetic Nanocarriers: Fe3O4-Hydroxyapatite/Polysuccinimide Hybrids for Enhanced Oral Bioavailability of Fluorouracil
20 Mar 2025 05:37 GMT
… for surgical intervention.3 Fluorouracil (5-FU), the … , for liver cancer treatment drugs, the concentration and … were purchased from Beyotime Biotechnology Co., Ltd. (Shanghai … behavior across different pharmaceutical compositions, highlighting underlying …