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AlzeCure Pharma Broadcasts Live Expert Event on Alzheimer's Around Highly Current Gamma-Secretase Modulators
12 Feb 2024 12:29 GMT
… s disease - Small molecule gamma-secretase modulators (GSMs) as promising disease … by gamma-secretase, a major limitation of first-generation gamma-secretase inhibitors … 39;s around highly current gamma-secretase modulators
SOURCE: AlzeCure Pharma
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Phoenix research center awarded $74.5M to study Alzheimer’s prevention
21 Nov 2024 12:08 GMT
… receive RG6289, Roche’s investigational gamma secretase modulator, an orally administered drug intended …
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The Antibody Drug Conjugate, Belantamab-Mafodotin, in the Treatment of Multiple Myeloma: A Comprehensive Review
06 Dec 2024 12:07 GMT
… : transmembrane activator and calcium modulator and cyclophilin ligand interactor ( … aICOS) receptor agonist), nirogacestat (a gamma-secretase inhibitor) and dostarlimab (a PD … impact.58 Furthermore, small-molecule gamma-secretase inhibitors (GSIs) can raise …
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Banner Alzheimer’s prevention trial receives $74.5 million federal grant
15 Nov 2024 00:45 GMT
… receive RG6289, Roche’s investigational gamma secretase modulator, an orally administered drug intended …
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Molecular imaging probe reveals Alzheimer's-related γ-secretase in rodents, macaques
18 Sep 2020 05:31 GMT
… to develop molecules that target gamma-secretase for the treatment and … first developed the concept of gamma-secretase modulators (GSMs), which preferentially reduce … molecule for better understanding how gamma-secretase contributes to AD pathogenesis.
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New Drug Shows Promise in Protecting Against Air Pollution-Linked Alzheimer’s Risk
12 Aug 2024 15:41 GMT
… type of drug called a gamma-secretase modulator. The team tested a specific … air pollution, Finch said.
“Because gamma secretase is needed for normal functions … amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606. Alzheimer’s …
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New drug GSM-15606 may guard against Alzheimer's risk from air pollution
12 Aug 2024 14:44 GMT
… type of drug called a gamma-secretase modulator. The team tested a specific … air pollution, Finch said.
Because gamma secretase is needed for normal functions … amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606. Alzheimer's …
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Drug protects against air pollution-related Alzheimer's signs in mice
12 Aug 2024 19:51 GMT
… type of drug called a gamma-secretase modulator. The team tested a specific … pollution, Finch said.
"Because gamma secretase is needed for normal functions …