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Mapping the Immune Landscape of Pancreatic Cancer: Insights for Targeted Precision Therapies
07 Feb 2025 10:35 GMT
… cell multi-omics approach integrates gene expression profiling with single-cell … insights gained from this extensive mapping are critical for understanding … Credits: Keywords Pancreatic cancer, Immune mapping, Precision therapy, Immunotherapy, Macrophages, …
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Mapping the Essential Genome of the Malaria Parasite Plasmodium knowlesi
06 Feb 2025 23:36 GMT
… mechanisms. Each identified gene offers potential targets … forward, this comprehensive genetic mapping will enable scientists to … (2025). The essential genome of Plasmodium knowlesi reveals … resistant malaria strainsessential genes in Plasmodium knowlesigenetic …
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Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
06 Feb 2025 17:10 GMT
… , Gene Ontology annotation enrichment analysis and Kyoto Encyclopedia of Genes and Genomes ( … biological mechanisms behind the identified genetic and proteomic associations. Future … . Phenome-wide Mendelian randomization mapping the influence of the plasma …
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Broken String Biosciences Launches Catalyst Program to Shorten Gene Editing Therapy Development by Months
06 Feb 2025 11:56 GMT
… technologies by delivering unbiased genome-wide insights, accurately detecting … gold standard for precise mapping of DNA breaks to … on- and off-target genetic edits, crucial for ensuring … Program, select partners with gene editing therapies in development …
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Exploring Core Genes Associated with Sepsis and Systemic Inflammatory Response Syndrome Using Single-Cell Sequencing Technology
06 Feb 2025 08:13 GMT
… cell number, gene number and genome comparison rate, … gene mapping. (A–C) The distribution and expression of top20 core genes … GCase activator linked to genetic disorders.35 PSAP, … supporting functional discovery in genome-wide experimental datasets. Nucleic …
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Transcriptional antitermination integrates the expression of loci of diverse phage origin in the chimeric Bartonella Gene Transfer Agent BaGTA
05 Feb 2025 23:12 GMT
… ., 2024). GTAs are mobile genetic elements, which emerged from defective … al., 2013). This specific genome architecture leads to ROR-driven … and evolutionary diversification of genes encoding the type IV … ; Sievers et al., 2011). Mapping of ChIP-Seq data was …
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Cognitive abilities: mapping the impact of DNA modifications
05 Feb 2025 03:47 GMT
… relies on the genetic information contained within the genes present in the … structures in the brain where gene expression is especially strong showed … intellectual disability.
Thanks to DNA mapping, these discoveries pave the way …
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Breeding Digest: Lamented Mare Mapping Out the Derby Trail
04 Feb 2025 22:05 GMT
Whether you consider it just a random squeaking of the hamster wheel, or evidence of some latent order awaiting our discovery, these Thoroughbreds certainly know how to make us stop and think about the strange operation of life.
Last Friday it was …
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New grant funds first-of-its-kind gene therapy to treat aggressive brain cancer
03 Feb 2025 22:07 GMT
… genetic data sets and identify “master regulators” within glioblastoma—key genes … trials.
Enhanced tumor mapping
Patients with aggressive brain … tumor to deliver the gene therapy and cellular treatment … to manufacture cell and gene therapies under the Food …
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Mapping the topographic organization of the human zona incerta using diffusion MRI
03 Feb 2025 18:59 GMT
… no corresponding homologues in mice. Genetic differences, such as primate-specific … patterns, respectively (Figure 1d-f).
Mapping continuous gradients of cortico-incertal … of the ZI through topographic mapping
Mapping the connectivity profile along the …