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High-Income Nations Lead, Others Lag in Cancer Care Equity
29 Jan 2025 07:02 GMT
… treatments, such as trastuzumab for breast cancer; erlotinib, gefitinib, and afatinib for non …
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Improving the Cytotoxic Activity of Hinokitiol from Drug-Loaded Phytosomal Formulation Against Breast Cancer Cell Lines
12 Oct 2024 09:01 GMT
… effective agents against breast cancer. The results demonstrated … effective agents for breast cancer treatment, warranting further … effective and targeted breast cancer therapeutics. Molecular docking … and senescence in gefitinib-resistant lung adenocarcinoma …
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Evolution of Personalized Cancer Care With Molecular Profiling
21 Jan 2025 23:54 GMT
… erlotinib (Tarceva) and gefitinib (Iressa) have improved … approach that has transformed breast cancer treatment, particularly for … patients with HER2-positive breast cancer. Additionally, newer … for HER2-positive metastatic breast cancer (CLEOPATRA): end- …
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Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer
29 Feb 2024 19:49 GMT
… microarray data of primary breast cancers of GSE25066 cohort, and … upregulation in triple-negative breast cancer (TNBC) compared to … NVP-ADW742 treatment, gefitinib treatment increased KDM4 demethylase … various cancers, including breast cancer, and promotes key …
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ArfGAP with the SH3 Domain, Ankyrin Repeat and PH Domain 1 Inversely Regulates Programmed Death-Ligand 1 Through Negative Feedback of Phosphorylated Epithelial Growth Factor Receptor and Activation of Nuclear Factor-Kappa B in Non-Small Cell Lung Cancer
20 Jan 2025 11:01 GMT
… dimethyl sulfoxide (DMSO). Gefitinib was purchased from BLD … Requirement for Arf6 in breast cancer invasive activities. Proc … novel targets to inhibit breast cancer invasive activities. EMBO … signaling pathway specific to breast cancer invasion and metastasis. …
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Molecular Biology Mechanisms and Emerging Therapeutics of Triple-Negative Breast Cancer
20 Sep 2023 16:40 GMT
… approach to characterizing breast tumors.26 Based on … portraits of human breast tumours. Nature. 2012;490 … medullary breast cancer is a subgroup of basal breast cancers. … gefitinib in taxane- and anthracycline-pretreated metastatic breast cancer. Breast Cancer …
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Dermatologic Adverse Events Following Afatinib in a Woman with Non-Small-Cell Lung Cancer: A Case Report
17 Jan 2025 14:00 GMT
… carcinoma (HNSCC), and breast cancer.3,4
EGFR inhibitors … (TKIs) (eg erlotinib, gefitinib, lapatinib, osimertinib, and afatinib … , followed by erlotinib, gefitinib, and osimertinib.12 Study … treated with lapatinib for breast cancer. Clin Exp Dermatol. …
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Research Progress on Molecular Subtyping and Modern Treatment of Triple-Negative Breast Cancer
24 Aug 2023 08:11 GMT
… stage breast cancer patients, patients were given either gefitinib … of triple negative breast cancers expressing CTLA-4. … -negative breast tumor growth by targeting GD2 + breast cancer stem … in triple-negative breast cancer. Breast Cancer Res Treat. 2022 …
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Roles of SPOCK1 in the Formation Mechanisms and Treatment of Non-Small-Cell Lung Cancer and Brain Metastases from Lung Cancer
15 Jan 2025 20:05 GMT
… apoptosis of T790M mutant gefitinib resistant cells. Knockdown … significant in triple-negative breast cancer, where Spock1 expression … poor prognosis in breast cancer clinical samples.15 … Epigenetic regulation of triple negative breast cancer (TNBC) by TGF-β …
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Application of Multifunctional Metal Nanoparticles in the Treatment of Glioma
15 Jan 2025 20:04 GMT
… fluoromagnetic nanoparticles for imaging of breast cancer mcf-7 cells. Adv Pharm … -delivery of GOLPH3 siRNA and gefitinib by cationic lipid-PLGA nanoparticles …
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