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Tucatinib in Combination With Trastuzumab Demonstrates Safety, Efficacy in Patients With HER2-Mutated Breast Cancer
27 Jan 2025 15:42 GMT
… BioPharma) and trastuzumab (Herceptin; Genentech) demonstrated clinically meaningful … (HER2)-mutated metastatic breast cancer (MBC).
Mutations in … HER2-mutated metastatic breast cancer: a phase 2 … with advanced HER2+ breast cancer (HER2CLIMB). Updated August …
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Adjuvant Trastuzumab Emtansine Improves Invasive Disease-Free Survival in Patients with HER2+ Early Breast Cancer
24 Jan 2025 23:48 GMT
… IDFS) compared with trastuzumab (Herceptin; Genentech) alone in patients … 2–positive (HER2+) early breast cancer (EBC). The data, published … patients with HER2-positive breast cancer who have residual … in residual HER2-positive breast cancer. N J Engl Med …
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Neoadjuvant Atezolizumab Plus Epirubicin Shows Safety, Efficacy in Treatment of HER2+ Early Breast Cancer
24 Jan 2025 18:47 GMT
… based chemotherapy.1
HER2+ breast cancer (BC) subtypes are aggressive … escalation immunotherapy regimen with trastuzumab (Herceptin; Genentech), pertuzumab (Perjeta; … modern immunotherapy to optimize breast cancer treatment—through improved effectiveness …
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Dr Montero on Unmet Treatment Needs for HER2+ Metastatic Breast Cancer
23 Jan 2025 23:38 GMT
… , MD, MBA, CPHQ, clinical director, Breast Cancer Medical Oncology Program, University Hospitals … breast cancer who had received at least 3 prior regimens, including trastuzumab (Herceptin … or other HER2-overexpressing non-breast cancers. In part b of the …
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FDA Approves Datroway for HER2-Negative Metastatic Breast Cancer
23 Jan 2025 15:26 GMT
… 47;HER2-negative positive breast cancer. The new targeted … such as Herceptin (trastuzumab). About 70% of breast cancer cases … positive, HER2-negative metastatic breast cancer treatment landscape, new … patients with metastatic breast cancer a new treatment …
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SHR-A1811 Maintains Efficacy, Safety in Pretreated HER2-Expressing/-Mutated Breast Cancer, Other Solid Tumors
23 Jan 2025 01:06 GMT
… breast tumors. PFS and DOR outcomes in patients with breast cancer … non-breast cancers compared with the overall breast cancer cohort … HER2-positive breast cancer, HER2-low breast cancer, colorectal cancer … antibody trastuzumab (Herceptin), a cleavable linker …
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Odzer on ERBB2 Copy Number Ratio as a Predictive Biomarker in HER2+ Breast Cancer
22 Jan 2025 19:33 GMT
… a predictive biomarker in metastatic breast cancer treated with conjugated and … -positive disease treated with trastuzumab (Herceptin), pertuzumab (Perjeta), and taxane … at the 2024 San Antonio Breast Cancer Symposium revealed significant associations …
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KN026 and Docetaxel Show Promise as First-Line Treatment for HER2+ Metastatic Breast Cancer
21 Jan 2025 17:32 GMT
… positive (HER2+) metastatic breast cancer (MBC), according … Comprehensive Cancer Network Breast Cancer Clinical Practice … Genentech) with trastuzumab (Herceptin; Roche), alongside taxane … patients with metastatic breast cancer. Updated September 21 …
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From Abemaciclib to Trastuzumab Deruxtecan: Highlights From the 2024 San Antonio Breast Cancer Symposium
20 Jan 2025 18:12 GMT
… anti-HER2 therapy of trastuzumab (Herceptin; Genentech, Inc) or trastuzumab … 47;www.oncologynewscentral.com/breast-cancer/trastuzumab-deruxtecan-outperforms-chemo … inavolisib approvals highlight advances in breast cancer care. Pharmacy Times. December …
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Adjuvant regimen extends survival in early HER2-positive breast cancer
16 Jan 2025 11:04 GMT
… treatments for early breast cancer were administered either … HER2-positive early breast cancer who receive neoadjuvant … HER2-positive metastatic breast cancer,” Geyer said. … HER2-positive breast cancer previously treated with trastuzumab [Herceptin, Genentech …