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ViiV Healthcare showcases leadership in long-acting injectables innovation at CROI 2025 with data on third-generation integrase inhibitor and highly potent capsid inhibitor against HIV-1
13 Mar 2025 09:11 GMT
ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer and Shionogi as shareholders, announced positive findings from two phase IIa proof-of-concept studies of investigational antiretroviral therapies VH4524184 (VH184) and …
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ViiV Healthcare showcases leadership in long-acting injectables innovation at CROI 2025 with data on third-generation integrase inhibitor (INSTI) and highly potent capsid inhibitor against HIV-1
11 Mar 2025 20:12 GMT
ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer and Shionogi as shareholders, today announced positive findings from two phase IIa proof-of-concept studies of investigational antiretroviral therapies VH4524184 (VH184) …
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ACTG Presents Study at CROI Demonstrating Increased Risk of Obesity and Cardiometabolic Disease After Switch to Integrase Inhibitor-Containing Regimen
09 Mar 2025 00:00 GMT
… that switching to an integrase inhibitor-based antiretroviral regimen increased … studies to determine whether taking integrase inhibitors leads to cardiovascular disease … disease risk, individuals on integrase inhibitor-containing regimens should be closely …
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Testing for HIV Integrase Inhibitor Resistance: 2025 and Beyond
22 Feb 2025 09:53 GMT
Date: March 5, 2025
Time: 8am EST (US) / 10am BRT (Brazil) / 3pm SAST (South Africa) / 6:30pm IST (India) / 9pm CST (Taiwan)
HIV drug resistance (HIVDR) can emerge with use of antiretroviral (ARV) drugs for HIV treatment and prevention. The …
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Integrase inhibitors not linked to neonatal weight
30 Jan 2025 20:11 GMT
… investigate whether ART, particularly integrase inhibitors, could similarly impact fetal … suggest a possible association between integrase inhibitors and maternal metabolic changes, … growth in patients on integrase inhibitors. While these medications remain …
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Effect of Machine Learning on Risk Stratification for Antiretroviral Treatment Failure in People Living with HIV
08 Apr 2025 15:04 GMT
… failure in the era of integrase inhibitors: a Spanish nationwide cohort. HIV … virological nonsuppression outcomes with initial integrase inhibitor-based regimens: a prospective RESPOND …
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US HHS describes HIV integrase inhibitors
09 Aug 2024 22:28 GMT
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ViiV Healthcare premieres early data showing antiviral activity against integrase resistance from its investigational, third-generation integrase inhibitor
23 Jul 2024 10:45 GMT
… . VH184, the first third-generation integrase inhibitor, with the potential for long … clinical trials of second-generation integrase inhibitors in treatment-experienced people living …
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Differences in Binding Affinity Between Integrase Inhibitors in HIV
09 Jul 2024 01:16 GMT
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Update on Emerging HIV Drug Resistance to Integrase Inhibitors...
08 Apr 2024 11:53 GMT
… Health Organization recommended using the integrase inhibitor, dolutegravir (DTG), in first- and … drug resistance to HIV-1 integrase inhibitors, with a focus on dolutegravir … the impact of resistance to integrase inhibitors on both public health and …