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Update on Emerging HIV Drug Resistance to Integrase Inhibitors...
08 Apr 2024 11:53 GMT
… Health Organization recommended using the integrase inhibitor, dolutegravir (DTG), in first- and … drug resistance to HIV-1 integrase inhibitors, with a focus on dolutegravir … the impact of resistance to integrase inhibitors on both public health and …
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Switching to integrase inhibitor may accelerate weight gain during menopause inHIV patients: Study
26 Mar 2024 21:42 GMT
Integrase strand transfer inhibitors (INSTIs) are associated with more significant weight gain in women with HIV (WWH) compared to men with HIV. Menopausal transition leads to changes in body composition.
A finding published in CROI, Conference on …
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Switch to an integrase inhibitor leads to greater weight during and after the menopause
11 Mar 2024 13:23 GMT
… before switching to an integrase inhibitor
Switching to an integrase inhibitor around the time … appear to suppress weight gain. Integrase inhibitors on the other hand, especially … , a switch to an integrase inhibitor was associated with significantly faster …
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The Future of HIV Treatment Is Injectable
05 Jun 2024 18:43 GMT
… HIV regimen that included an integrase-inhibitor, which targets an enzyme HIV …
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More evidence that integrase inhibitors don’t raise heart disease risk
10 Nov 2023 09:46 GMT
… regimens. People starting integrase inhibitors had significantly higher baseline … of integrase inhibitor recipients and 6% of non-integrase inhibitor recipients … integrase inhibitor-containing regimens – thereby taking account of the drugs integrase inhibitors …
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Theratechnologies Presents Data at ID Week Showing Tesamorelin Reduces Visceral Adipose Tissue (VAT) and Liver Fat in People with HIV on Integrase Inhibitors (INSTIs)
13 Oct 2023 11:30 GMT
… adiposity that commonly occur with integrase inhibitors.” Tesamorelin, a growth hormone- … with HIV who are on integrase inhibitors, potential treatment strategies will … people with HIV treated with integrase inhibitor based regimens. Forward-Looking …
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Do Integrase Inhibitors Raise the Risk for Cardiovascular Disease?
19 Sep 2023 21:26 GMT
… about the link between integrase inhibitors—especially dolutegravir—and metabolic … and several studies have implicated integrase inhibitors specifically. Excess weight—especially … , but not for other integrase inhibitors (for example, bictegravir or …
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Integrase inhibitors more likely to be linked to depression and suicidality than other HIV drugs
24 Aug 2023 11:30 GMT
… are any differences between integrase inhibitors.
Integrase inhibitors include dolutegravir (Tivicay, … raltegravir (Isentress).
As integrase inhibitors are the most widely … with suicidality than other integrase inhibitors.
Depression developed an average …
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Exavir Therapeutics Receives $3M Award from NIH / NIAID to Advance Ultra-Long-Acting Integrase Inhibitor XVIR-110
22 Aug 2023 11:16 GMT
… an ultra-long-acting HIV integrase inhibitor with a preclinical profile that … our ultra-long-acting HIV integrase inhibitor,” said Brian Kearney, Chief Scientific …
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NIAID grant supports development of ultra-long-acting HIV integrase inhibitor XVIR-110
23 Aug 2023 13:00 GMT