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Antibody-Based Therapeutics in Small Cell Lung Cancer: A Narrative Review
15 Apr 2025 14:11 GMT
… to SN-38, an irinotecan metabolite with TOP1 inhibition … patients with small cell lung cancer. Lung Cancer. 2018;115:116–120 … patients with small cell lung cancer. Lung Cancer. 2020;147:237–243 … in metastatic small cell lung cancers and patient-derived models. …
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Bristol Myers Squibb Receives Positive CHMP Opinion for Perioperative Regimen of Neoadjuvant Opdivo® (nivolumab) and Chemotherapy Followed by Surgery and Adjuvant Opdivo for Resectable Non-Small Cell Lung Cancer in Patients with Tumor Cell PD-L1...
28 Mar 2025 13:11 GMT
… four tumor types: lung cancer, bladder cancer, esophageal … pathologic response.
About Lung Cancer
Lung cancer is the leading … fluoropyrimidine, oxaliplatin, and irinotecan. This indication is … lung cancer; Checkmate 816–neoadjuvant non-small cell lung cancer, …
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Bristol Myers Squibb Announces Opdivo® Plus Chemotherapy as the First and Only Neoadjuvant-Only Immuno-Oncology Therapy to Demonstrate Statistically Significant and Clinically Meaningful Overall Survival in Resectable Non-Small Cell Lung Cancer
19 Feb 2025 12:09 GMT
… positive) non-small cell lung cancer (NSCLC).
OPDIVO® (nivolumab … fluoropyrimidine, oxaliplatin, and irinotecan. This indication is … metastatic non-small cell lung cancer, in combination with … lung cancer; Checkmate 816–neoadjuvant non-small cell lung cancer, …
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Metabolomic Analysis, Antiproliferative, Anti-Migratory, and Anti-Invasive Potential of Amlodipine in Lung Cancer Cells
19 Feb 2025 00:32 GMT
… lung cancer (NSCLC) forms approximately 80% of all lung cancer … with amlodipine.
Discussion
Lung cancer, specifically NSCLC, continues … pathway after treating lung cancer cells A549 with … N. Simvastatin enhances irinotecan-induced apoptosis in prostate …
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Drug-Eluting Beads Bronchial Arterial Chemoembolization Combined with Immunotherapy Resulted in Pathological Complete Response of Squamous Cell Lung Cancer: A Case Report
18 Dec 2024 16:06 GMT
… include doxorubicin, pirarubicin, irinotecan, oxaliplatin, cisplatin, gemcitabine … drug for treating lung cancer. Importantly, epirubicin … arterial chemoembolization in lung cancer patients with hemoptysis … assessment of lung cancer resection specimens …
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New Therapies Expand Options in Recurrent Small Cell Lung Cancer
14 Nov 2024 00:03 GMT
… to managing recurrent small cell lung cancer (SCLC), especially in patients who … we had were topotecan and irinotecan, but as of May of …
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New therapies lurbinectedin and tarlatamab bring hope for small cell lung cancer treatment
07 Nov 2024 05:16 GMT
… small cell lung cancer (SCLC), one of the least curable lung cancers, is about … carboplatin arm.
“In small cell lung cancer, atezolizumab showed efficacy independent of … drugs, including topotecan, belotecan, and irinotecan.
“The side effects of lurbinectedin …
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Current Status and Future Prospects of TROP-2 ADCs in Lung Cancer Treatment
05 Nov 2024 16:00 GMT
… Characteristics of Patients with Lung Cancer
Lung cancer is a complex and … the active metabolite of irinotecan, a topoisomerase I inhibitor … in the treatment of lung cancers, and a clinical … novel therapeutic approach in lung cancer. Lung Cancer. 2022;163:96– …
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Real-World Outcomes with Lurbinectedin in Second Line and Beyond for Extensive Stage Small Cell Lung Cancer in Korea
30 Oct 2024 08:51 GMT
… lung cancer (SCLC) accounts for approximately 10– 15% of all lung cancers … confirmed small cell lung cancer (SCLC) who … line chemotherapy regimens (topotecan, irinotecan + platinum (IP), and … stage small cell lung cancer. Clin Lung Cancer. 2023;24( …
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Jazz's almost-withdrawn lung cancer drug Zepzelca extends life on top of Roche's Tecentriq
15 Oct 2024 19:25 GMT
… in extensive-stage small cell lung cancer (ES-SCLC).
Zepzelca, used in … /m2 in combination with irinotecan, versus physician’s choice of …