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Update on Pulmonary Toxicity Induced by New Breast Cancer Treatments
21 Jan 2025 18:11 GMT
… the two phase III trials (ASCENT trial: cough, 17% and … drug-related lung toxicity was lower than that for ADCs.
Lapatinib
Lapatinib … Xu B. Advances in Medical Treatment of Breast Cancer in 2022 … #47;/Www.Fda.Gov/Drugs/Fda-Warns-about-Rare-Severe …
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ANDA Approvals - New Drug Applications and 505(b)(2) Applications: Third Quarter
15 Nov 2024 22:16 GMT
Approval Date
Reference Listed Drug
Generic Drug Name
NDA Holder
…
Endari
L-Glutamine
Emmaus Medical
Novitium Pharma
215647
07… ;16/2024
Tykerb
Lapatinib Ditosylate
Novartis
Teva
217968
… 2024
Tarceva
Erlotinib HCl
OSI Pharmaceuticals
Hikma
203843
09…
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Identification of Cellular Senescence-Related Critical Genes and Molecular Classification and Revealing the Drug-Resistant Therapeutic Effect of IGFBP2 in Chronic Myeloid Leukemia
06 Nov 2024 09:32 GMT
… with the advancement of medical research, the role … treatment, we conducted a prediction of the therapeutic sensitivity of chemotherapy drugs … Cytarabine, Dasatinib, and Lapatinib (Figure 4B). The … traits and guiding clinical treatment, with critical CSRG …
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Gupta Discusses T-DM1’s Role in HER2+ Breast Cancer Treatment
23 Oct 2024 02:10 GMT
… University Department of Medicine, Division of Medical Oncology, discusses the … was the first antibody-drug conjugate (ADC) to be … remains a mainstay of treatment for patients with HER2 … and lapatinib [Tykerb] as based on the EMILIA trial [NCT00829166 …
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Prediction of Pharmacokinetic Drug–Drug Interactions Involving Anlotinib as a Victim by Using Physiologically Based Pharmacokinetic Modeling
14 Oct 2024 16:10 GMT
… 18 Despite the drug label stating that anlotinib … contribute to optimizing drug treatment strategies, individualized medication, and improving … of its metabolism. Pharmaceutics. 2022;14(3):477 … and carbamazepine on lapatinib pharmacokinetics in healthy …
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A Gluconeogenesis-Related Genes Model for Predicting Prognosis, Tumor Microenvironment Infiltration, and Drug Sensitivity in Hepatocellular Carcinoma
04 Oct 2024 16:26 GMT
… , gefitinib, dasatinib, afatinib, lapatinib, pictilisib, navitoclax, temozolomide, osimertinib … sensitivity to six medications, among which oxaliplatin … , patient prognosis, and drug treatment strategies in HCC. Our … controlled phase II-III trial. J Clin Oncol. …
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Less Toxic, More Personalized Treatments on the Horizon in HER2+ Breast Cancer
12 Sep 2024 22:52 GMT
… shared Dempsey, breast medical oncologist at Baptist Health … approaches, less toxic treatments, promising trial results, and more. … that reason, ongoing trials are evaluating treatments with CNS activity … as neratinib [Nerlynx] and lapatinib [Tykerb] caused a …
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Breast Cancer Screening and Treatment Update
18 Sep 2024 16:27 GMT
… drugs, primarily targeted therapies, have recently been FDA approved for treatment. … lapatinib) product information. East Hanover, NJ: Novartis Pharmaceutical Corp; March 2022.
29. Nerlynx (neratinib) product information. Los Angeles, CA: Puma Biotechnology …
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Amiloride Sensitizes Prostate Cancer Cells to the Reversible Tyrosine Kinase Inhibitor Lapatinib by Modulating ERBB3 Subcellular Localization.
12 Sep 2024 11:00 GMT
… progression. The FDA-approved HER2 inhibitor lapatinib has been … and thus protected from lapatinib which affect membrane … 2. Amiloride combined with lapatinib significantly increased apoptosis but … combination of amiloride and lapatinib could target HSPC …
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Comparative Analysis and Future Prospects of Human Epidermal Growth Factor Receptor 2 (HER2) and Trophoblast Cell-Surface Antigen 2 (Trop-2) Targeted Antibody-Drug Conjugates in Breast Cancer Treatment
17 Sep 2024 03:07 GMT
… in clinical trials, most notably in the ASCENT trial, which … Strategies and Pathway Regulation. Pharmaceuticals. 2024;17(2). doi … efficiently inhibits growth of lapatinib insensitive breast cancer. … -38 antibody-drug conjugate for the treatment of diverse …
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