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Study could help predict treatment response for KRASG12C-mutant non-small cell lung cancer
01 Feb 2025 04:10 GMT
… non-small cell lung cancer, a type of lung cancer known for … outcomes for patients with KRAS-mutant cancers."
Eric … and P30CA076292), the Moffitt Lung Cancer Center of Excellence and … mutant non–small cell lung cancer. Clinical Cancer Research. doi …
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Moffitt study finds key biomarker to predict KRASG12C inhibitor effectiveness in lung cancer
01 Feb 2025 00:14 GMT
… non-small cell lung cancer, a type of lung cancer known for … outcomes for patients with KRAS-mutant cancers.”
The new … and P30CA076292), the Moffitt Lung Cancer Center of Excellence and Revolution … -mutant non–small cell lung cancer
Article Publication Date
21 …
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Moffitt Research Identifies Crucial Biomarker for Predicting Effectiveness of KRASG12C Inhibitors in Lung Cancer Treatment
31 Jan 2025 23:02 GMT
… better outcomes for patients with KRAS-mutant cancers.” The promise of … lung cancer therapeuticsbiomarker for lung cancer treatmentcancer biomarker discoveryclinical implications of KRASG12CKRASG12C inhibitors in lung cancerMoffitt …
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Exploring Zoldonrasib, Pan-RAS Inhibitors, and Future KRAS Therapies
30 Jan 2025 20:33 GMT
… -9805) for patients with KRAS G12D pancreatic ductal adenocarcinoma based … types. KRAS G12D makes up about 4% of lung cancer cases. … mutations that develop after KRAS G12D therapy, based on … several years ago, are other KRAS mutations. So, can combination …
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Tissue-Based NGS May Help Determine Relevant Gene Copy Number Gain Cutpoint for HER2/KRAS/MET in NSCLC
29 Jan 2025 16:03 GMT
… published in Clinical Lung Cancer.1
The copy … driver-positive when excluding KRAS mutations,” investigators wrote. … comparisons,” investigators wrote. “KRAS mutations (36.87% no … KRAS and MET copy-number gain in nonsmall cell lung cancer. Clin Lung Cancer …
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Watson Unpacks the Potential Clinical Impact of High-Level MET, HER2, and KRAS Amplifications in NSCLC
28 Jan 2025 22:59 GMT
… gain in non–small cell lung cancer (NSCLC) tumors, and … BRAF TKIs exist in lung cancer, and they’re approved … negative prognostic association. For KRAS, that association was present … KRAS and MET copy-number gain in nonsmall cell lung cancer. Clin Lung Cancer …
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RAS(ON) Inhibitor Zoldonrasib Is Safe, Shows Early Activity Signals in KRAS G12D–Mutated PDAC
24 Jan 2025 21:49 GMT
… activity in patients with KRAS G12D–mutated pancreatic … advanced solid tumors harboring KRAS G12D mutations. To … cancer, non–small cell lung cancer, sinonasal adenocarcinoma, melanoma of … inhibitor in patients with KRAS G12D pancreatic ductal adenocarcinoma …
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APAC takes centre-stage in AI-driven drug discovery
31 Jan 2025 12:27 GMT
… in discovering novel drugs for lung cancer treatment.
Leading the charge in … molecules targeting the cancer-linked KRAS protein, previously deemed undruggable. This …
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Revisit Every OncLive On Air Episode From January 2025
31 Jan 2025 00:21 GMT
… adenocarcinoma or non–small cell lung cancer (NSCLC) harboring NRG1 gene fusion … clinically relevant thresholds for MET, KRAS, and HER2 gene copy number … a subgroup of meaningfully HER2-, KRAS-, and MET-amplified cancers that …
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3 Biotech Stocks Revolutionizing Healthcare
30 Jan 2025 16:04 GMT
… treatment of adult patients with KRAS G12C-mutated metastatic colorectal cancer … with extensive-stage small cell lung cancer whose disease has progressed on …