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Genetic Insights Into Lipid Traits and Lipid-Modifying Drug Targets in Pregnancy Complications: A Two-Sample Mendelian Randomization Study
31 Jan 2025 06:09 GMT
… their primary pharmacological effects: (1) LDL-C-lowering drugs targeting … of exposure on mediator), βMO (effects of mediator on outcome), and … of exposure on mediator; βMO, effects of mediator on outcome; β … of statins. Annu Rev Pharmacol Toxicol. 2005;45:89 …
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Comanche Biopharma Awarded Innovation Passport Designation by the U.K. Innovative Licensing and Access Pathway (ILAP) Steering Group for CBP-4888, an Investigational siRNA Drug Candidate for the Treatment of sFlt1-mediated Preterm Preeclampsia
30 Jan 2025 10:00 GMT
… consequences
A novel investigational drug candidate, CBP-4888 … placenta, a key pathogenic mediator of preeclampsia
CONCORD, Mass., … Comanche Biopharma’s investigational drug candidate for the treatment … as a key pathogenic mediator of preeclampsia. When …
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Gamers with lower social skills are more likely to make impulsive in-game purchases
02 Feb 2025 12:35 GMT
A new study published in Computers in Human Behavior explores how competitive attitudes influence in-game impulse purchases, focusing on the psychological mechanisms that drive spending in gaming environments. The study found that while competitiveness …
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City, firefighters bringing in mediator for contract negotiations
24 Jan 2025 18:12 GMT
… union are bringing in a mediator to help work through final … , pensions and a new random drug testing policy. Adding a second …
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Targeting PLOD2 Suppresses Invasion and Metastatic Potential in Radiorecurrent Prostate Cancer - Beyond the Abstract
01 Feb 2025 00:46 GMT
… PLOD2 expression with the pharmacological agent PX-478, we … by inhibiting its upstream mediator HIF1α, this finding nevertheless … proof-of-concept for pharmacologically inhibiting PLOD2 to reduce … metalloproteinase inhibition? Nat Rev Drug Discov 13, 904-927, …
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Mediating Effects of Stress on Fibromyalgia Syndrome Development
30 Jan 2025 15:00 GMT
Photo Credit: Axel Kock
The following is a summary of “Early-life adversity as a predictor of fibromyalgia syndrome: the central role of perceived stress over endocrine stress indicators,” published in the January 2025 issue of Pain by Beiner et al.
The …
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Is Lifetime Cancer Risk Established before Birth?
29 Jan 2025 20:30 GMT
The results of a study in mice by Van Andel Institute (VAI) scientists suggest that a person’s lifetime risk for cancer may begin before they are even born. Headed by J. Andrew Pospisilik, PhD, chair of VAI’s department of epigenetics, the researchers …
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Car crash claims one, five injured on Lagos-Ibadan Expressway
02 Feb 2025 12:49 GMT
… ago
Operatives of the National Drug Law Enforcement Agency (NDLEA) have … career as a litigator, certified mediator, and arbitrator specialising in conflict …
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Zulum donates N30m to family of slain soldier
02 Feb 2025 12:41 GMT
… ago
Operatives of the National Drug Law Enforcement Agency (NDLEA) have … career as a litigator, certified mediator, and arbitrator specialising in conflict …
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The ANC’s immunity cloak is wearing thin
02 Feb 2025 03:35 GMT
… and adherence.
So, while the drugs will still be physically available … the role of peacemaker or mediator. And if South Africa prefers …
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