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Aldeyra Therapeutics Receives Complete Response Letter from the U.S. Food and Drug Administration for the Reproxalap New Drug Application for the Treatment of Signs and Symptoms of Dry Eye Disease
03 Apr 2025 12:34 GMT
… .S. Food and Drug Administration (FDA) for the resubmission … NDA stating that at least one additional symptom trial … clinical trials.
About Aldeyra
Aldeyra Therapeutics is a biotechnology … of intravitreal methotrexate for the potential treatment of retinitis …
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Telitacicept: A New Therapy for the Treatment of Optic Neuromyelitis Spectrum Disease Associated with Other Autoimmune Disorders
03 Apr 2025 11:17 GMT
… National Medical Products Administration for the treatment of … , multicentre randomised controlled trials are warranted to further … based on target-mediated drug distribution for RC18, … methotrexate: results of a Phase II, randomized, placebo-controlled trial …
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Subcutaneous Methotrexate Superior to Oral Version in Key Areas for Psoriasis
02 Apr 2025 14:26 GMT
… from the selected trials—including information regarding trial designs, therapy outcomes … and Efficacy of Subcutaneous Methotrexate in the Treatment of Adult Patients With … Dermal Microdialysis Showing Higher Methotrexate Bioavailability in Psoriasis Plaques …
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Neutrophil Activity, Immune Imbalance May Drive Biologic Resistance in Psoriasis
04 Apr 2025 14:17 GMT
… University College of Medicine’s Gil Medical Center in … used a cross-sectional trial design, focusing their research … months of conventional treatment at least using methotrexate, cyclosporine, phototherapy, … to an alternative biologic drug, resulting from an …
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Grip Strength Impairment and Neuropathic-Like Pain as Predictors of Functional Decline in Hand Osteoarthritis
04 Apr 2025 11:24 GMT
… analgesics, and anti-inflammatory treatments.
Outcomes and questionnaires self- … were being treated with methotrexate but none were taking … is up to the medical doctor in charge of the … treated with antiepileptics or antidepressants.47
In our cohort, …
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VTEs with JAK Inhibitors Similar Between Those with Atopic Dermatitis, General Population
03 Apr 2025 20:22 GMT
… ). They used a case–control trial design, implementing SNDS data covering … single dispensation of a systemic treatment—methotrexate, cyclosporine, tralokinumab, dupilumab, or a … exposed to systemic atopic dermatitis drugs.
There were 48 cases of …
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Atopic Dermatitis (AD) Across Ages: Identifying and Treating Flares in Children and Adults
03 Apr 2025 02:23 GMT
… for prompt intervention
Treatment Strategies
First-Line Therapy … after bathing
Anti-inflammatory Treatments:
Topical corticosteroids (TCS): … UVA1)
Systemic immunosuppressants (cyclosporine, methotrexate, azathioprine)
Biologics (dupilumab, tralokinumab …
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Orca-T Boosts cGVHD-Free Survival vs Allo-HSCT in Advanced Hematologic Malignancies
02 Apr 2025 20:14 GMT
… an associate professor of medicine (Blood and Marrow … Abdominal Transplantation) at Stanford Medicine in California.
Compared with … treatment during the study, and 1 patient received tacrolimus and methotrexate … FDA in 2025.
“Due to the success of this trial, …
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Certain biologics May Reduce Infection Risk among elderly with Psoriasis: JAMA
04 Apr 2025 16:01 GMT
… published in Journal of American Medical Association suggests that biologics targeting … to the systemic medication prescribed to them, including:
Methotrexate
Other older systemic … versus non-use of respective treatments:
Methotrexate: RR = 0.95 (95% CI …
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Comprehensive Analyses of Single-Cell and Bulk RNA Sequencing Data From M2 Macrophages to Elucidate the Immune Prognostic Signature in Patients with Gastric Cancer Peritoneal Metastasis
03 Apr 2025 20:50 GMT
… to bosutinib, gefitinib, lenalidomide and methotrexate (Figure S7B). In addition, we … conclusion, these drugs may be promising for the treatment of GCPM.
Discussion … of the medical research council adjuvant gastric infusional chemotherapy (MAGIC) trial. JAMA …
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