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Korean pharma and biotech to unveil innovative cancer research at AACR 2025
03 Apr 2025 07:53 GMT
… number of Korean pharmaceutical and biotech companies are set to … olaparib and XAV939 in preclinical trials. With U.S. FDA Orphan Drug … the company expects the trial to finish enrollment soon … mutant cancers, ID11916 for treatment-resistant prostate cancer, and …
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New structural and mechanistic understanding for cancer drug design
03 Apr 2025 06:11 GMT
… researchers develop new anti-cancer drugs.
"RAD52 is a … Biology, Carver College of Medicine, University of Iowa Health … with the PARP inhibitor olaparib remain disease free for … Spies, PhD, professor of drug discovery and experimental therapeutics in …
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AstraZeneca's Imfinzi receives US FDA approval for patients with muscle─invasive bladder cancer
01 Apr 2025 05:17 GMT
… the Food and Drug Administration (FDA) after securing Priority … Professor of Medicine, Director of Genitourinary Medical Oncology, The … phase III trial evaluating perioperative Imfinzi as treatment for patients … followed by Lynparza (olaparib) and Imfinzi is …
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Therapeutic Targeting in Ovarian Cancer: Nano-Enhanced CRISPR/Cas9 Gene Editing and Drug Combination Therapy
29 Mar 2025 11:12 GMT
… FDA-approved PARP inhibitors for ovarian cancer include olaparib … and potential for personalized medicine. By attaching specific … Other Drugs in Ovarian Cancer Treatment
Anticancer Drugs in … bacterial functions fuels diverse biotechnologies. Front Cell Infect …
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When a Cancer Drug Shortens Life: Lessons From ARIEL4
25 Mar 2025 15:18 GMT
… when the experimental drug does harm, trials are stopped early … inhibitors in this setting, olaparib and niraparib, both of … in the Department of Medicine at Brigham and Women… financial toxicities of cancer treatment, clinical trial methods, and supportive …
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First Patent Dosed With Pocenbrodib in Trial for Metastatic Prostate Cancer
22 Mar 2025 01:31 GMT
… abiraterone acetate), Lynparza (olaparib) or Pluvicto (177Lu … serious underlying medical, psychiatric, psychological, familial … treatment-related complications are also excluded.
More Study Details and Drug … information on the trial, use the trial ID, NCT06785636, …
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Pembrolizumab and olaparib in a cisplatin-refractory testicular cancer patient with a high TMB: first case report.
21 Mar 2025 15:34 GMT
… (choriocarcinoma) treated with pembrolizumab and olaparib based on high programmed death … weeks after starting pembrolizumab and olaparib, b-hCG increased steadily … targeted treatment possibilities might present a helpful step toward precision medicine in …
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Emerging ADCs, Biomarker-Driven Treatments, and Diagnostic Advancements Take Center Stage at the SGO Annual Meeting
21 Mar 2025 14:45 GMT
… MD, University of Pittsburgh Medical Center Hillman Cancer Center … of antibody-drug conjugates (ADCs), biomarker-driven treatment selection, … evaluating pembrolizumab (Keytruda) plus olaparib (Lynparza) in advanced … and Risk Reduction Trials Are of Increasing …
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Olaparib Plus Abiraterone in Asian Patients With Metastatic Castration-Resistant Prostate Cancer: PROpel Subset Analysis.
20 Mar 2025 09:57 GMT
In the phase 3 PROpel trial (NCT03732820) patients with metastatic … combination of olaparib plus abiraterone as an important first-line treatment for … School of Medicine, Sagamihara, Kanagawa, Japan., Saitama Medical Center, Saitama Medical University, …
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Pathos AI Doses First Patient in Phase 1b/2a Clinical Trial of Pocenbrodib, a CBP/p300 Inhibitor
20 Mar 2025 12:00 GMT
… Chief Medical Officer. "Our precision medicine approach … with abiraterone acetate, olaparib or 177Lu-PSMA-617 … treatments. About Pathos AI
Pathos is a clinical-stage biotechnology … 2 clinical trials. Through partnerships with pharmaceutical companies, …