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Tecentriq Falls Short in Phase III Trial in Post-Surgery Triple-Negative Breast Cancer Patients
06 Feb 2025 20:43 GMT
… 80 mg/m2 of paclitaxel each week for 12 weeks … Atezolizumab for Early Triple-Negative Breast Cancer: The ALEXANDRA/IMpassion030 Randomized … Patients With Operable Triple-Negative Breast Cancer (IMpassion030). ClinicalTrials.gov. Updated August …
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FDA approves fam-trastuzumab deruxtecan-nxki for unresectable or metastatic HR-positive, HER2-low or HER2-ultralow breast cancer
06 Feb 2025 20:35 GMT
… with membrane staining) breast cancer, as determined by an … 0 with membrane staining) breast cancer for treatment with Enhertu … 60%, nab-paclitaxel 24%, or paclitaxel 16%).
The major … patients with HER2-low breast cancer assessed by blinded independent …
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Eribulin Proves Noninferior to Taxane as Combination Partner With Trastuzumab and Pertuzumab in HER2+ Breast Cancer
06 Feb 2025 18:11 GMT
… paclitaxel in patients with HER2-positive locally advanced or metastatic breast cancer … -positive locally advanced breast cancer or metastatic breast cancer,” the study authors … locally advanced/metastatic breast cancer: the randomized noninferiority phase …
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Pembrolizumab Combo Enhances Response Rate in ER+/HER2– Breast Cancer
06 Feb 2025 01:02 GMT
… grade 3 high-risk invasive breast cancer, according to results from … [ER-positive/HER2-negative breast cancer], a significantly higher percentage of … mg m-2 of paclitaxel once weekly for the … -stage, ER+/HER2− breast cancer: a randomized phase 3 trial …
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Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab resistant HER2 positive breast cancer
05 Feb 2025 20:06 GMT
… transcription and accelerated breast cancer tumorigenesis(21). … positive breast cancer patients received trastuzumab plus paclitaxel, … of breast cancer, different subtypes of breast cancer might … methylation contributes to breast cancer tumorigenesis and drug …
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FDA OKs T-DXd Companion Diagnostic in HER2-Low Metastatic Breast Cancer
05 Feb 2025 01:03 GMT
… positive, HER2-ultralow metastatic breast cancer eligible for fam-trastuzumab … The rising incidence of metastatic breast cancer, particularly among younger populations, … oral capecitabine, intravenous paclitaxel, or intravenous nab-paclitaxel.
The primary …
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FDA Approves Companion Diagnostic for T-DXd in HER2-Ultralow Metastatic Breast Cancer
03 Feb 2025 19:35 GMT
… The rising incidence of metastatic breast cancer, particularly among younger populations … comprising capecitabine, nab-paclitaxel (Abraxane), or paclitaxel. Stratification factors included … with HER2-ultralow metastatic breast cancer eligible for Enhertu. News …
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Advances in Ultrasound-Targeted Microbubble Destruction (UTMD) for Breast Cancer Therapy
03 Feb 2025 12:15 GMT
… of highly malignant breast cancers, including TNBC, … breast cancer cells under both static and dynamic conditions. Moreover, paclitaxel … treatment of malignant breast tumors, the key … breast tumours using ultrasound responsive microbubbles loaded with paclitaxel …
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Nanoparticles Modulating the Immune Microenvironment in Breast Cancer Treatment
01 Feb 2025 10:18 GMT
… breast tumor treatment.66,67 Therefore, nanoparticle-based combination therapies represent promising breast cancer … to other cancers, breast tumors are often characterized by … paclitaxel in combination with alpha-PD1 induces tumor remission of breast cancer …
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The Expanding Role of CDK 4/6 Inhibitors in Breast Cancer Treatment
31 Jan 2025 18:18 GMT
… For endocrine-susceptible breast cancers, the next line … cycles of chemotherapy (paclitaxel or vinorelbine) with … metastatic breast cancer. Presented at: San Antonio Breast Cancer Symposium; … metastatic breast cancer: phase 1b study. NPJ Breast Cancer. 2022; …