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Dr Yu on Factors for PARP Inhibitor Decision-Making in Metastatic Prostate Cancer
09 Apr 2025 00:44 GMT
… is definitively better between any PARP inhibitor [vs] another.… surrounding the tolerability of PARP inhibitors and how their … support the use of PARP inhibitors in select patients … personalized approach to selecting PARP inhibitors for eligible patients …
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Impact Therapeutics divulges new PARP-1 inhibitors
08 Apr 2025 18:00 GMT
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Insights on BRCA2 gene enhance understanding of PARP inhibitor efficacy in cancer treatment
03 Apr 2025 22:53 GMT
… gene determines how effectively PARP inhibitors can kill cancer cells … for DNA repair, which PARP inhibitors are designed to block … damage sites, explaining why PARP inhibitors work only in … BRCA2-deficient tumor cells to PARP inhibitors.
First study author …
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Study sheds light on how major cancer gene influences the success of PARP inhibitors
03 Apr 2025 19:31 GMT
… precision cancer drugs called PARP inhibitors.
Recently published in … the mechanism by which PARP inhibitors have their effect. … -deficient tumor cells to PARP inhibitors.
"Moving forward … variable BRCA2 activity dictates PARP inhibitor efficacy points to …
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The love of reading celebrated at Wolcott's Reading Fair and PARP Fest
29 Mar 2025 12:56 GMT
… Street School Book Fair and PARP Fest.
PARP stands for Pick A … , we would all wear our PARP shirts."
Why is reading …
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Making Sense of PARP Inhibitors
24 Mar 2025 20:15 GMT
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PARP Inhibitor and ARPI Combinations Are at the Forefront of Investigations in mCRPC
20 Mar 2025 17:24 GMT
… NCT03395197) was the first PARP inhibitor plus ARPI combination … -proficient disease.
Could PARP inhibitors move up earlier … overlapping bidirectionality between both PARP and androgen receptors, so … the combination therapy over PARP monotherapy because there …
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US and Canadian researchers describe new PARP-1 inhibitors
18 Mar 2025 23:11 GMT
… poly(ADP-ribose) polymerase 1 (PARP-1; ARTD1) inhibitors reported to …
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Dr Nathanson on the Role of Reversion Mutations in PARP Inhibitor Resistance in Breast Cancer
13 Mar 2025 21:52 GMT
… genes will respond effectively to PARP inhibition. Notably, missense mutations, … mutations and their role in PARP inhibitor resistance, emphasizing the importance … patients with breast cancer receiving PARP inhibition, Nathanson explains. Previously, it …
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The Landscape of PARP Inhibitors in Solid Cancers
01 Mar 2025 15:45 GMT
… without bevacizumab, as treatment in PARP inhibitor-naïve platinum-sensitive relapsed … receptor inhibitor-induced “BRCAness” and PARP inhibition are synthetically lethal for … of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant …