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BRCA mutations and prostate cancer: should urologist improve daily clinical practice?
21 Apr 2025 08:34 GMT
To evaluate BRCA1-2 (breast cancer) detection in men with high risk PCa, including the oncological consequences for the patient and family members.
From January 2023 to December 2024, 52 men (median age 73 years;) with confirmed PCa diagnosis underwent …
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Can a Polygenic Risk Score Help Catch More Prostate Cancers?
18 Apr 2025 12:18 GMT
… the detection of clinically significant prostate cancer that conventional screening may miss … as intermediate- or high-risk (Gleason score ≥ 7) per National Comprehensive Cancer … of a polygenic score for prostate cancer screening,” commented Michael Inouye, …
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Robotic prostatectomy for large-volume prostates in prostate cancer: a retrospective analysis of 50 cases (>100 ml).
18 Apr 2025 08:17 GMT
… volume (> 100 ml) prostate cancer.
A retrospective analysis was … (> 100 ml) prostate cancer who underwent robotic radical … 0.35 ± 0.21). Gleason scores were: 15 scored 7, … prostatectomy for large-volume prostate cancer, despite its surgical challenges …
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Clinical Outcomes and Genomic Alterations in Gleason Score 10 Prostate Cancer.
16 Apr 2025 16:16 GMT
Background: Gleason score (GS) 10 prostate cancer (PC) is a highly aggressive …
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Identification of a 5-Gene Signature Panel for the Prediction of Prostate Cancer Progression - Beyond the Abstract
15 Apr 2025 22:19 GMT
… (PSA) levels, Gleason score, and the extent … variables associated with prostate cancer progression, including … prognosis associated with prostate cancer progression, including … . Localized prostate cancer: Learn More – Low-risk prostate cancer: Active …
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Precision Active Surveillance: Leveraging Genomic Testing and CCR Scores in Prostate Cancer Management
15 Apr 2025 16:20 GMT
… following:
Genomic Testing in Prostate Cancer Active Surveillance
Key Considerations for … risk stratification
Look beyond traditional Gleason scores and prostate- specific antigen … represents a paradigm shift in prostate cancer management, moving toward truly …
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We're proof prostate cancer screening can save men's lives - by spotting tumours with NO symptoms
15 Apr 2025 13:14 GMT
… for a nationwide prostate cancer screening programme, similar … patients diagnosed with prostate cancer who have repeatedly … 39;
The charity Prostate Cancer Research estimates that initially … the Gleason score, which rates how aggressive the prostate cancer is …
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Apalutamide Boosts 24-Month OS in Real-World Population With Metastatic Castration-Sensitive Prostate Cancer
14 Apr 2025 18:04 GMT
… PSA levels, and initial Gleason score. The proportion of patients … approves-enzalutamide-metastatic-castration-sensitive-prostate-cancer
Armstrong AJ, Szmulewitz RZ, … high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall …
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Impact of ISUP grade group on cancer-specific mortality in radical prostatectomy-treated prostate cancer patients with organ-confined disease.
14 Apr 2025 13:45 GMT
… prostatectomy (RP).
RP organ-confined prostate cancer (PCa) patients were identified (Surveillance … with available primary and secondary Gleason score (GS).
Overall, 61 172 … Division of Oncology, Gianfranco Soldera Prostate Cancer Lab, IRCCS San Raffaele …
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Genetic test outperforms PSA and MRI in spotting deadly prostate cancer early
11 Apr 2025 01:20 GMT
… histopathologist and graded using the Gleason score system. Diagnoses were classified … Comprehensive Cancer Network (NCCN) prostate cancer risk categories.
Participants diagnosed with … 43.2% had aggressive cancers (Gleason score ≥7). MRI also had limitations …
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