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Reviewing Second-Line RCC Therapy After Immune Checkpoint Inhibition
10 Apr 2025 22:48 GMT
… line therapies used in renal cell carcinoma (RCC)?
Benjamin Garmezy, MD … showing that this drug is acting exactly … renal cell carcinoma after progression with previous immune checkpoint inhibitor treatment … for advanced renal-cell carcinoma. N Engl J Med. 2024; …
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Opinion: The National Cancer Institute’s Investigational New Drug program is imperative for public good
10 Apr 2025 18:14 GMT
… partners with drug companies to develop drugs in the … public interest. A special review panel of external drug … therapies for patients with renal cell carcinoma and neuroendocrine tumors, … for decades, developed drugs in collaboration with industry …
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Combination of MLo-1508 with sunitinib for the experimental treatment of papillary renal cell carcinoma.
09 Apr 2025 11:41 GMT
Renal cell carcinoma (RCC) is the 14th most incident … treatment alternatives are urgently needed to tackle disease management and drug resistance … that, different RCC cell lines were treated with both drugs, alone or …
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Soluble TIM-3, Likely Produced by Myeloid Cells, Predicts Resistance to Immune Checkpoint Inhibitors in Metastatic Clear Cell Renal Cell Carcinoma - Beyond the Abstract
08 Apr 2025 19:55 GMT
… of metastatic clear cell renal cell carcinoma (mccRCC) has significantly … growing number of treatment options and the lack … at the time of treatment. Furthermore, plasma biomarkers … in metastatic clear cell renal cell carcinoma. Journal of Experimental …
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Tumor Response to Immune-Oncology Therapy Despite High-Dose Steroid Intervention in a Patient With Papillary Renal Cell Carcinoma and Immune-Related Myasthenia Gravis.
08 Apr 2025 09:53 GMT
… altered the treatment landscape for various cancers, including renal cell carcinoma (RCC). Unfortunately, … . Even while giving corticosteroid treatment for myasthenia gravis, the … patient exhibited a striking treatment response, with substantial tumor …
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HIF-2α Inhibitors Make Significant Inroads in Renal Cell Carcinoma
07 Apr 2025 17:22 GMT
… wave of therapeutic approaches in renal cell carcinoma (RCC) will target hypoxia-inducible factor … and ischemia. Yale J Biol Med. 2007;80(2):51-60 … sunitinib in first-line treatment of advanced renal cell carcinoma (RCC): a randomized, open-label …
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Activity of lenvatinib-based therapy in previously treated patients with metastatic renal cell carcinoma: A European multicenter study (LENVA-LAT).
07 Apr 2025 10:58 GMT
… (ICI) combination therapy in renal cell carcinoma (RCC) remains unknown. We aimed … (ORR) and time-to-treatment failure (TTF). Secondary endpoints … of 3 previous lines of treatment, including ICIs (90. … regimens or lines of treatment. With a median follow …
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Off-Label Use of First-Line Immunotherapy for Metastatic Renal Cell Carcinoma.
07 Apr 2025 10:58 GMT
… Food and Drug Administration (FDA) for patients with metastatic renal cell carcinoma (mRCC) in …
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Immunogenomic Properties Predict Exceptional Responses to Immune Checkpoint Inhibition in RCC
08 Apr 2025 19:23 GMT
… in Nature Cancer.1
“Treatment [for patients with RCC] has evolved greatly … sunitinib in patients with treatment-naive advanced RCC also demonstrated an association … ) versus sunitinib (S) for advanced renal cell carcinoma (RCC). J Clin Oncol. 2024;42 …
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Clinical and pathological outcomes of deferred nephrectomy in patients with metastatic and locally advanced RCC after immune checkpoint inhibitors.
07 Apr 2025 10:58 GMT
… checkpoint blockade (ICB) in metastatic renal cell carcinoma remains controversial, with limited data … nephrectomy (dCN) after ICB-based treatment, focusing on the radiologic and … with metastatic or locally advanced RCC who underwent dCN after ICB …
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