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Bispecific Antibodies, Novel Combinations Highlight Continued Treatment Evolution in Follicular Lymphoma
26 Oct 2024 12:10 GMT
… assistant professor of medicine at Harvard Medical School and a … significance of the growing treatment options for follicular lymphoma. … in combination with rituximab (Rituxan) and lenalidomide (Revlimid) … [as monotherapy]. This trial was looking at the …
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Acalabrutinib Plus Venetoclax/Rituximab Yields 100% ORR in Treatment-Naive Mantle Cell Lymphoma
22 Oct 2024 19:10 GMT
Treatment with the combination of acalabrutinib (Calquence), venetoclax (Venclexta), and rituximab (Rituxan … the Division of Cancer Medicine at The University … .
The phase 1b trial evaluated acalabrutinib in combination … withholding of any study drug in 71.4% …
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New Data Shed Light on the Efficacy of BTK Inhibitors in the CLL Treatment Paradigm
21 Oct 2024 20:44 GMT
… (CLL) following prior treatment with covalent BTK inhibitors … assistant professor of medicine at Harvard Medical School and an … acquired mutations.
What other trials are seeking to combine … , venetoclax, and rituximab [Rituxan]. These were patients who had …
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Jaypirca Plus Venclexta With or Without Rituxan May Be Beneficial in r/r CLL
10 Oct 2024 18:16 GMT
… and Rituxan (rituximab; PVR), researchers have reported.
The phase 1b BRUIN trial … researchers reported.
Eight patients discontinued treatment early, five in the PV … deaths, one each after discontinuing treatment for progressive disease, after discontinuing …
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Acalabrutinib Earns FDA Priority Review in Untreated Mantle Cell Lymphoma
03 Oct 2024 19:41 GMT
… has set a Prescription Drug User Fee Act date … trial (NCT02972840) assessing acalabrutinib in combination with bendamustine and rituximab (Rituxan … co-director of Clinical Trials at The University of … the FDA to provide patients this potential new treatment as …
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Acalabrutinib Receives FDA Priority Review in Frontline MCL
03 Oct 2024 18:13 GMT
… lymphoma (MCL).
The Prescription Drug User Fee Act (PDUFA) … lymphoma. Data from the ECHO trial [NCT02972840] showed [acalabrutinib] … plus bendamustine and rituximab (Rituxan; BR) reduced the risk … approval from the FDA for the treatment of adult patients …
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Acalabrutinib Gets Priority Review for Frontline MCL Treatment
04 Oct 2024 14:22 GMT
… new drug application for acalabrutinib (Calquence) for the frontline treatment … quarter of 2025.
The FDA based its decision on … of bendamustine and rituximab (Rituxan), led to a 27% … .
“Data from the ECHO trial showed [acalabrutinib] plus chemoimmunotherapy …
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FDA Grants Priority Review to Acalabrutinib in Treatment-Naive Mantle Cell Lymphoma
03 Oct 2024 16:12 GMT
… acalabrutinib, bendamustine, and rituximab (Rituxan; BR; n = 299) … Data from the ECHO trial showed [acalabrutinib] plus … the FDA to provide patients this potential new treatment … ;www.fda.gov/drugs/;resources-information-approved-drugs/fda-grants- …
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Bishop Discusses Post-Steroid Treatment Approaches for Chronic GVHD
24 Sep 2024 18:19 GMT
… MD
MODERATOR
Professor of Medicine
Director, Hematopoietic Stem Cell … photopheresis [ECP], rituximab [Rituxan], and ibrutinib [Imbruvica] still … treatment], even though most if not all of these drugs … of the trials…the [phase 3 iNTEGRATE trial (NCT02959944) …
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Chugai Pharma, Zenyaku Kogyo's anti─CD20 monoclonal antibody, Rituxan receive Japanese approval to treat refractory steroid─resistant nephrotic syndrome
25 Sep 2024 08:41 GMT
… ., Ltd. and Chugai Pharmaceutical Co., Ltd. announced 0that … steroid treatment, which is the first-choice drug. Steroid … an investigator-initiated clinical trial targeting patients with childhood … that Rituxan can further contribute to the treatment of …