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Solanezumab does not slow cognitive decline in patients with Alzheimer’s disease
10 Nov 2023 12:24 GMT
… be candidates for intervention. Solanezumab is an immunoglobulin G1 … as to understanding whether solanezumab as compared with placebo … as they demonstrate that solanezumab does not slow cognitive … this study demonstrates that solanezumab did not slow cognitive …
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Solanezumab for Preclinical Alzheimer's: Phase 3 Data
20 Jul 2023 15:25 GMT
… assigned to receive placebo or solanezumab for 4.5 years. … numerically greater decline in the solanezumab group.
The lack of … type of monoclonal antibody used. Solanezumab doesn't bind … ARIAs) with edema in the solanezumab group; there were two cases …
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Lilly's A4 study of solanezumab to treat Alzheimer's disease fails to meet primary and secondary endpoints
10 Mar 2023 06:26 GMT
… concludes our clinical development of solanezumab and indicates that targeting soluble … , numerically favoring placebo compared with solanezumab.
36.1% of participants starting … safety profile observed in previous solanezumab phase 3 studies. Amyloid-Related …
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Lilly Provides Update on A4 Study of Solanezumab for Preclinical Alzheimer's Disease
08 Mar 2023 23:11 GMT
… symptomatic Alzheimer's disease
Solanezumab targets soluble amyloid beta, and … concludes our clinical development of solanezumab and indicates that targeting soluble … , numerically favoring placebo compared with solanezumab.
36.1% of participants starting …
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Lilly's Solanezumab Fails In Alzheimer's Prevention Trial
09 Mar 2023 03:16 GMT
… . Participants were randomized to either solanezumab or placebo and then treated … concluded its clinical development of solanezumab and indicated that targeting soluble … population.
According to the company, Solanezumab binds only to soluble amyloid …
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Eli Lilly Alzheimer's treatment solanezumab failed to slow disease progression
09 Mar 2023 05:11 GMT
… 's treatment candidate solanezumab after the antibody failed to … slow disease progression.
Solanezumab's failure is … with Alzheimer's.
Solanezumab did not clear or halt … director of the study.
Solanezumab was designed to target plaque …
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Eli Lilly announces DIAN─TU study of solanezumab fails to meet primary endpoint
11 Feb 2020 06:10 GMT
… pursue a submission for solanezumab in people with dominantly … not impact the ongoing solanezumab Anti-Amyloid Treatment in … efficacy analysis included 50 solanezumab and 40 placebo participants. … 39;s disease."
Solanezumab is an investigational anti- …
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Lilly Announces Topline Results for Solanezumab from the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) Study
10 Feb 2020 14:39 GMT
… does not impact the ongoing solanezumab Anti-Amyloid Treatment in Asymptomatic … primary efficacy analysis included 50 solanezumab and 40 placebo participants. The … detection of the disease.
About Solanezumab
Solanezumab is an investigational anti-amyloid …
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Eli Lilly: DIAN-TU Study With Solanezumab Fails To Meet Endpoint - Quick Facts
10 Feb 2020 06:26 GMT
… DIAN-TU Study showed that solanezumab did not meet the primary … to pursue a submission for solanezumab in people with dominantly inherited … does not impact the ongoing solanezumab Anti-Amyloid Treatment in Asymptomatic …
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Eli Lilly's solanezumab fails to slow cognitive decline in Alzheimer's
29 Jan 2018 16:35 GMT
… monoclonal antibody-based drug solanezumab did not significantly slow … 39;s disease.
“Clearly solanezumab at this dose in this … lead to cell damage. Solanezumab was supposed to interfere … results did “directionally favored solanezumab.”
The failure of the …