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FDA Approval of Cabozantinib for Pancreatic and Extra-Pancreatic Neuroendocrine Tumors Opens the Door to a New Standard Option
25 Apr 2025 19:41 GMT
… those who may have somatostatin receptor–positive or – … associate professor of medicine at Harvard Medical School, both … pause treatment or reduce the dose. In the trial, … ;www.fda.gov/drugs/;resources-information-approved-drugs/fda-approves- …
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Human medicines European public assessment report (EPAR): Oczyesa, octreotide, Status: Opinion
25 Apr 2025 16:13 GMT
…
Oczyesa is a hybrid medicine2 of Sandostatin, which has … and in a different pharmaceutical form. Studies have demonstrated … responded to and tolerated treatment with somatostatin analogues.
The recommended … clinical tests and clinical trials for a reference …
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CAR T, Targeted Therapies, Others as Treatment Options on the Horizon in NETs
24 Apr 2025 20:41 GMT
… trials make significant progress to help provide more efficacious and targeted treatments … made it to clinical trial. We’re very excited … an exciting outcome.
Another trial is focused on a … primarily targeting a peptide called somatostatin. There is a subset …
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Crinetics Pharmaceuticals Announces European Medicines Agency (EMA) Validation of Marketing Authorization Application (MAA) and Orphan Drug Designation (ODD) for Paltusotine in Acromegaly
27 Mar 2025 20:05 GMT
… trials that evaluated paltusotine for the treatment of acromegaly in medically … Drug Administration (FDA) of the New Drug Application (NDA) for paltusotine for the treatment … Pharmaceuticals
Crinetics Pharmaceuticals is a clinical stage pharmaceutical …
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Human medicines European public assessment report (EPAR): Xermelo, telotristat ethyl, Date of authorisation: 17/09/2017, Revision: 16, Status: Authorised
11 Apr 2025 16:33 GMT
… benefits of adding Xermelo to treatment have been shown in one … with somatostatin analogues alone. Xermelo was compared with placebo (a dummy treatment … about 3 weeks after starting treatment.
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Crinetics Pharmaceuticals to Report First Quarter 2025 Financial Results on May 8, 2025
11 Apr 2025 12:00 GMT
… About Crinetics Pharmaceuticals
Crinetics Pharmaceuticals is a clinical stage pharmaceutical company focused … once-daily, oral, selective somatostatin receptor type 2 (SST2) … entities resulting from in-house drug discovery efforts, including additional …
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Crinetics Pharmaceuticals Announces April 2025 Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
10 Apr 2025 21:04 GMT
… Crinetics Pharmaceuticals
Crinetics Pharmaceuticals is a clinical stage pharmaceutical company … -daily, oral, selective somatostatin receptor type 2 (SST2 … development for the treatment of congenital adrenal … from in-house drug discovery efforts, including …
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Behind the FDA Approval: Cabozantinib for Advanced Neuroendocrine Tumors
02 Apr 2025 16:36 GMT
… Trials Network. It was a randomized, double-blinded, placebo-controlled trial … therapy targeting the somatostatin receptor, molecularly … of treatment efficacy.
References:
1. FDA approves … fda.gov/drugs/;resources-information-approved-drugs/fda …
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Mainline Biosciences discovers new peptide-drug conjugates for cancer
02 Apr 2025 18:46 GMT
… described peptide-drug conjugates consisting of peptide targeting somatostatin receptors covalently bound … to be useful for the treatment of cancer.
BioWorld Science Cancer …
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OncLive’s FDA Approval Report: The Regulatory Rundown for March 2025
03 Apr 2025 02:31 GMT
… Medical Campus, contextualized the use of tislelizumab as a frontline treatment … tumor site, grade, somatostatin receptor expression, and … 3 NIAGARA trial (NCT03732677) supported the FDA’s … and Harvard Medical School, detailed clinical trials investigating …