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U.S. Food and Drug Administration Approves Opdivo® (nivolumab) plus Yervoy® (ipilimumab) as a Treatment for Patients with Previously Untreated Microsatellite Instability-High or Mismatch Repair Deficient Unresectable or Metastatic Colorectal Cancer1
08 Apr 2025 19:43 GMT
… .S. Food and Drug Administration (FDA) approved Opdivo® (nivolumab … previously treated with sorafenib. This indication is … access to BMS medicines during their treatment journey. BMS … development and commercialization of pharmaceutical products. All statements …
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Management of Regorafenib-Induced Hand-Foot Skin Reaction with Topical Chinese Medicine and Urea Ointment: A Case Report and Literature Review
08 Apr 2025 15:05 GMT
… in multiple clinical trials.5 Hand-foot … sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial … 002
28. Chinese Medical Doctor Association Bone Tumor Professional … , and novel drug delivery routes. Pharmaceutics. 2023;15( …
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Q2 2025: 7 FDA Decisions to Watch in the Realm of Oncology
05 Apr 2025 03:55 GMT
… announced the FDA accepted its … trial (NCT03215706) showing the combination significantly improved overall survival compared to sorafenib … TRUST-II (NCT04919811) trials, taletrectinib achieved an … Drug-Administration-sBLA-Acceptance-for-First-Line-Treatment …
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Camrelizumab Combo Doubles 5-Year Survival in Phase 3 Lung Cancer Trial
02 Apr 2025 23:47 GMT
… antibody developed by Hengrui Pharmaceuticals, binds with high affinity … , the Food and Drug Administration (FDA) issued a second complete … as a first-line treatment for unresectable or metastatic … 15.2 months with sorafenib. Median progression-free survival …
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Folic Acid-Targeted Liposome-Based Nanoparticle Loaded with Sorafenib for Liver Cancer Therapy
29 Mar 2025 11:12 GMT
… kits purchased from TransGen Biotech (Beijing, China) were … phase III clinical trials, melanoma, and other … sorafenib-induced cardiovascular toxicity: mechanisms and treatment implications. DrugDes … their biomedical applications. Pharmaceutics. 2019;11(8): …
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Dual-Mode Treatment of Hepatocellular Carcinoma Using RGD Cyclopeptide-Modified Liposomes Loaded with Ce6/DOX
27 Mar 2025 13:21 GMT
… drug-carrying liposomes were purchased from Nanjing Dongna Biotechnology … number: 81271677), Medical Science and Technology … therapies in clinical trials: a systematic … sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, Phase 3 trial …
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A guide to kinase inhibitors in biotech: From cancer breakthroughs to autoimmune innovations
26 Mar 2025 23:00 GMT
… colitis
Stage: Multiple clinical trials
Brepocitinib was originally developed … conducting a phase 3 trial for dermatomyositis, a … as therapies age. Biotech companies are already developing … approach to cancer treatment. Drugs such as sorafenib, lenvatinib, and …
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Exelixis Announces U.S. FDA Approval of CABOMETYX® (cabozantinib) for Patients with Previously Treated Advanced Neuroendocrine Tumors
26 Mar 2025 13:26 GMT
… Drug Administration (FDA) has approved CABOMETYX® (cabozantinib) for the treatment … Trials in Oncology for conducting the CABINET trial, to the FDA … been previously treated with sorafenib; for adult and … rights to Takeda Pharmaceutical Company Limited for …
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Junshi Biosciences Announces Approval of sNDA for Toripalimab in Combination with Bevacizumab for 1st-line Treatment of Advanced Hepatocellular Carcinoma
24 Mar 2025 03:53 GMT
… Medical Products Administration (“NMPA”) has approved the supplemental new drug … compared to the standard treatment with sorafenib. In September 2024 … completed pivotal clinical trials evaluating the safety and … of a Chinese pharmaceutical company through its …
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FDA Issues Second Camrelizumab/Rivoceranib CRL in Hepatocellular Carcinoma
21 Mar 2025 22:54 GMT
… open-label phase 3 trial randomly assigned 543 patients … of patients discontinued treatment with sorafenib due to a … News release. Jiangsu Hengrui Pharmaceuticals Co., Ltd. May 17 … Therapeutics announces FDA acceptance of new drug application resubmission …