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RNA Sequencing Identifies Novel Signaling Pathways and Potential Drug Target Genes Induced by FOSL1 in Glioma Progression and Stemness
05 Apr 2025 08:44 GMT
… reached the mainstream of cancer treatment.
IFIT1, an interferon-induced protein … considered as a potential drug target for glioblastoma treatment.86 Additionally, in … al. ITGA5 Predicts Dual-Drug Resistance to Temozolomide and Bevacizumab in Glioma …
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Experimental therapy for brain cancer gives ‘hope’; will be investigated in upcoming trial
04 Apr 2025 10:21 GMT
… glioblastoma.
An international trial will start enrolling … University School of Medicine and principal investigator … rather than just testing drugs and seeing them … adjuvant treatment, including radiation and temozolomide. However, temozolomide will …
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FDA Gives RPDD to NEO100 for Pediatric-Type Diffuse High-Grade Glioma
03 Apr 2025 17:04 GMT
The FDA has granted rare pediatric …
A phase 1b dose-finding trial (NCT06357377), which has yet … maximum standard pediatric dose of temozolomide (Temodar)—90 mg/ … currently receiving another investigational drug or other anticancer treatments, or have a …
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Candel Therapeutics Announces Publication of Phase 1b Clinical Trial Data on the Combination of CAN-2409 and Nivolumab plus Standard of Care in Newly Diagnosed High-Grade Glioma Patients
01 Apr 2025 12:01 GMT
… neurosurgery, radiotherapy, and temozolomide), in patients with … trial confirm and extend previous observations in clinical trials … Professor at Harvard Medical School, Candel Scientific … FDA has also granted Orphan Drug Designation to CAN-2409 for the treatment …
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FDA Approves Cabozantinib in Pancreatic/Extra-Pancreatic Neuroendocrine Tumors
26 Mar 2025 16:21 GMT
… the phase 3 CABINET trial (NCT03375320), in which … England Journal of Medicine showed that treatment with cabozantinib … vs 15% received prior temozolomide (Temodar)–based therapies. … and Drug Administration (FDA) accepted the supplemental New Drug Application …
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Allegations of unnecessary chemotherapy treatments at University Hospital Coventry under investigation
26 Mar 2025 14:55 GMT
… were allegedly given unnecessary chemotherapy treatments at University Hospital Coventry … to alleged unnecessarily prolonged treatments of chemotherapy drug temozolomide (TMZ) from the … in 2023 – to the General Medical Council.
Paralegal Becky Addison from …
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Brindley Twist Tafft and James steps in to offer support to patients affected by extended use of temozolomide chemotherapy
13 Mar 2025 09:55 GMT
… and Warwickshire’s leading medical negligence practitioners, is offering … to treatment guidelines.
The extended use of temozolomide has … to those impacted. Medical negligence law allows patients … substandard care by medical professionals to seek compensation …
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A Mechanistic Study of the Feasibility of Ursodeoxycholic Acid in the Treatment of Colon Adenocarcinoma
12 Mar 2025 16:07 GMT
… the mechanism of drug multi-target treatment of diseases from … purchased from Beijing Huizhiheyuan Biotechnology Co. HCT116, SW620 … role in resistance to temozolomide through regulation of p53… analysis, and further clinical trials and animal experiments need …
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Orphelia Pharma explores other pathways for paediatric cancer treatment
12 Mar 2025 10:44 GMT
… secure access to this treatment for paediatric cancer patients … . Laurent Martin, Chief Pharmaceutical Affairs Officer at Orphelia … trials, subject to agreement by relevant authorities.
KIZFIZO (temozolomide … Orphan Drug Designation from the EMA and the FDA.
…
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Allarity Therapeutics Announces Phase 2 Trial of Stenoparib in Combination with Temozolomide for Recurrent Small Cell Lung Cancer Fully Funded by the US Veterans Administration
06 Mar 2025 13:00 GMT
… a Phase 2 clinical-stage pharmaceutical company dedicated to developing stenoparib … patients on the drug combination treatment across 11 VA medical centers. It … stenoparib-temozolomide combination trial from the U.S. Food and Drug Administration (FDA), the …