-
Data Monitoring Committee OKs INVINCIBLE-3 Sarcoma Trial Continuation
28 Jan 2025 23:28 GMT
… release from the drug’s developer, Intensity … trial have been obtained from the FDA, Health Canada, the European Medicines … pazopanib (Votrient) tablets, trabectedin (Yondelis), or eribulin mesylate … Additionally, grade 3 treatment-related adverse events (TRAEs …
-
Sonnet BioTherapeutics to expand trial of SON-1010 with trabectedin for solid tumours
22 Jan 2025 18:59 GMT
US-based biotechnology company Sonnet BioTherapeutics … in combination with trabectedin, a chemotherapeutic drug approved for certain … combination with trabectedin as a new and improved treatment for … ) for platinum-resistant ovarian cancer.
Sign up for our …
-
Sonnet BioTherapeutics Expands Phase 1 SB101 Trial to Evaluate Combination of SON-1010 with Trabectedin in Certain Sarcomas
21 Jan 2025 14:05 GMT
… treatment of STS. We believe that combining trabectedin … on platinum-resistant ovarian cancer (PROC) (NCT05756907). … biotechnology company with a proprietary platform for developing targeted biologic drugs … peptides, antibodies and vaccines. Sonnet’s lead …
-
FDA clears Axcynsis’ AT03-65 IND for CLDN6-positive solid tumours
16 Jan 2025 12:32 GMT
… Food and Drug Administration (FDA) has cleared the investigational new drug application ( … to CLDN6.
The upcoming trial will assess the therapy’s … , is a derivative of trabectedin, a chemotherapy approved in … develops targeted therapies for cancer treatment.
-
Improved Antitumor Efficiency of N4-Tetradecyloxycarbonyl Gemcitabine-Loaded Liposomes for Pancreatic Cancer Chemotherapy
11 Dec 2024 12:56 GMT
… purchased from Yangtze River Pharmaceutical Co., Ltd. (Zhejiang … Committee of Institute of Medicinal Biotechnology [License Number: SYXK … challenges in pancreatic cancer treatment. Adv Drug Deliv Rev. … and trabectedin combinations in pancreatic cancer cells. …
-
Intensity Therapeutics Presents INT230-6 Phase 1/2 Data in Sarcoma and an Overview of its Ongoing Global Randomized Phase 3 Sarcoma Trial (“INVINCIBLE-3 Study”) in a Late-Breaking Session at the 2024 Annual Connective Tissue Oncology Society Meeting (C …
19 Nov 2024 07:10 GMT
… : pazopanib tablets, trabectedin, and eribulin mesylate … S. FDA, Health Canada, the European Medicines Agency … biotechnology company whose novel engineered chemistry enables aqueous cytotoxic-containing drug … treatment paradigm and turn many deadly cancers …
-
Four Cases with FUS/CHOP Fusion Gene Products Positive Myxoid Liposarcoma Responding Effectively to Trabectedin Monotherapy
16 Nov 2024 11:48 GMT
… School of Medicine, Dentistry, and Pharmaceutical Sciences and … shown that prolonged trabectedin treatment leads to the … Randomized Phase III trial of trabectedin versus doxorubicin-based … trabectedin: a pooled analysis of two phase II clinical trials. Cancer …
-
Combination chemo helps people with Leiomyosarcoma cancer live longer – Study finds
12 Nov 2024 10:56 GMT
… were severe, leading many doctors to consider them to be … patient care,” the National Cancer Institute (NCI) of the … adding trabectedin (Yondelis) to doxorubicin as an initial treatment for … the New England Journal of Medicine.
So what is Leiomyosarcoma …
-
Combination of doxorubicin-trabectedin with trabectedin improves leiomyosarcoma outcomes
12 Oct 2024 14:45 GMT
… the previous phase three trials, which focused on … metastasis, contraindication to trial drugs, and participation in another … -trabectedin combination for first-line treatment with immediate trabectedin … PD
©2024 2 Minute Medicine, Inc. All rights reserved …
-
The Dual Role of NRF2 in Colorectal Cancer: Targeting NRF2 as a Potential Therapeutic Approach
03 Sep 2024 16:53 GMT
… extracted from traditional Chinese medicine Poria cocos) combined … subsequent Phase I clinical trial.107 A prospective … X, Zeng J. Trabectedin induces ferroptosis via regulation of … on colon cancer cell survival: evidence of drug treatment association with …