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Application of Multifunctional Metal Nanoparticles in the Treatment of Glioma
15 Jan 2025 20:04 GMT
… medical imaging and cancer treatment. The excellent biocompatibility and drug … of Minocycline and Vorinostat Targets the Tumor Microenvironment … Based on Nano-Biotechnology in the Treatment of Glioma. … Gold Nanoparticles. Mol Pharmaceut. 2019;16:2430–2444 …
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Prescient Therapeutics welcomes US FDA allowance of...
23 Dec 2024 00:16 GMT
… potential to address key unmet medical needs in T-cell lymphomas … -100 has Orphan Drug Designation from the US FDA for all T … associated with standard care treatment vorinostat.
The Phase 1b trial remains open, with …
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Discovery of a Novel and Potent Dual-Targeting Inhibitor of ATM and HDAC2 Through Structure-Based Virtual Screening for the Treatment of Testicular Cancer
19 Nov 2024 13:24 GMT
… in clinical cancer treatment, including vorinostat, romidepsin, and … Committee of China Pharmaceutical University (permit number … trials.16 In clinical practice, the HDAC inhibitor vorinostat … developing anti-cancer drugs. Comput. Struct. Biotechnol. J. …
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The Advances in the Development of Epigenetic Modifications Therapeutic Drugs Delivery Systems
18 Oct 2024 12:49 GMT
… profiles of these medications, ultimately leading to improved treatment outcomes.
Figure … clinical trials were isohydroxamic acid analogs.69 The FDA-approved drug vorinostat first … trial data for nano-based epigenetic drugs in breast cancer treatment …
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Epigenetic drugs show 375% increase in Series A venture financing in 2024
25 Sep 2024 16:53 GMT
… vorinostat) and Acrotech Biopharma’s Beleodaq (belinostat). However, these drugs … The FDA’s approval of Vertex Pharmaceuticals’ … -based Epicrispr Biotechnologies launched with … drugs play a key part in precision medicine by providing tailored treatments …
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Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
04 Jul 2024 21:08 GMT
… children1,2. Years of clinical trials have revealed that conventional chemotherapy … (20 ng/ml, Shenandoah Biotechnology, 100-146), human EGF (20 … media, and subjected to drug treatment for 3 days (Vorinostat) or 8 days …
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Unravel Biosciences enters partnership to trial Pitt Hopkins Syndrome treatment
12 Jun 2024 17:48 GMT
… -concept trial of vorinostat (RVL-001), a potential treatment for … Pitt Hopkins Syndrome (PTHS).
The drug … using Unravel’s BioNAV drug discovery platform as … rapidly advance promising drugs into clinical testing …
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Unravel Biosciences Receives FDA Orphan Drug Designation for Vorinostat (RVL-001) as a Treatment for Rett Syndrome
28 May 2024 23:01 GMT
… Food and Drug Administration (FDA) for vorinostat (RVL-001) as a treatment for Rett … clinical trial material manufacturing for use in upcoming Rett syndrome clinical trials … platform access to foundation and biotech partners to accelerate and clinically …
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Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
26 Mar 2024 16:59 GMT
… to note that three compounds (vorinostat, Y-33075, and GSK-1070916 … on the proteome due to drug treatment could reveal new information concerning … -HRP secondary antibody (Santa Cruz Biotechnology, sc-2004).
Cell cycle synchronization …
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New trial hints at a possible HIV cure approach: Wake up latent virus hiding in the body, then kill it" data-before-rewrite-localise="/health/hiv/new-trial-hints-at-a-possible-hiv-cure-approach-wake-up-latent-virus-hiding-in-the-body- …
22 Mar 2024 19:40 GMT
… be wiped out.
The treatment isn't enough … David Margolis, a professor of medicine, microbiology and immunology, and … hiding
With modern antiretroviral drugs, doctors can prevent HIV from … team attempted this with vorinostat, a drug shown to "wake …